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KLRG1 expression on natural killer cells is associated with HIV persistence, and its targeting promotes the reduction of the viral reservoir.
Astorga-Gamaza A, Perea D, Sanchez-Gaona N, Calvet-Mirabent M, Gallego-Cortés A, Grau-Expósito J, Sanchez-Cerrillo I, Rey J, Castellví J, Curran A, Burgos J, Navarro J, Suanzes P, Falcó V, Genescà M, Martín-Gayo E, Buzon MJ. Astorga-Gamaza A, et al. Among authors: sanchez cerrillo i. Cell Rep Med. 2023 Oct 17;4(10):101202. doi: 10.1016/j.xcrm.2023.101202. Epub 2023 Sep 22. Cell Rep Med. 2023. PMID: 37741278 Free PMC article.
COVID-19 severity associates with pulmonary redistribution of CD1c+ DCs and inflammatory transitional and nonclassical monocytes.
Sánchez-Cerrillo I, Landete P, Aldave B, Sánchez-Alonso S, Sánchez-Azofra A, Marcos-Jiménez A, Ávalos E, Alcaraz-Serna A, de Los Santos I, Mateu-Albero T, Esparcia L, López-Sanz C, Martínez-Fleta P, Gabrie L, Del Campo Guerola L, de la Fuente H, Calzada MJ, González-Álvaro I, Alfranca A, Sánchez-Madrid F, Muñoz-Calleja C, Soriano JB, Ancochea J, Martín-Gayo E; REINMUN-COVID and EDEPIMIC groups. Sánchez-Cerrillo I, et al. J Clin Invest. 2020 Dec 1;130(12):6290-6300. doi: 10.1172/JCI140335. J Clin Invest. 2020. PMID: 32784290 Free PMC article. Clinical Trial.
Poly I:C and STING agonist-primed DC increase lymphoid tissue polyfunctional HIV-1-specific CD8+ T cells and limit CD4+ T-cell loss in BLT mice.
Calvet-Mirabent M, Claiborne DT, Deruaz M, Tanno S, Serra C, Delgado-Arévalo C, Sánchez-Cerrillo I, de Los Santos I, Sanz J, García-Fraile L, Sánchez-Madrid F, Alfranca A, Muñoz-Fernández MÁ, Allen TM, Buzón MJ, Balazs A, Vrbanac V, Martín-Gayo E. Calvet-Mirabent M, et al. Eur J Immunol. 2022 Mar;52(3):447-461. doi: 10.1002/eji.202149502. Epub 2022 Jan 8. Eur J Immunol. 2022. PMID: 34935145 Free article.
Antiretroviral therapy duration and immunometabolic state determine efficacy of ex vivo dendritic cell-based treatment restoring functional HIV-specific CD8+ T cells in people living with HIV.
Calvet-Mirabent M, Sánchez-Cerrillo I, Martín-Cófreces N, Martínez-Fleta P, de la Fuente H, Tsukalov I, Delgado-Arévalo C, Calzada MJ, de Los Santos I, Sanz J, García-Fraile L, Sánchez-Madrid F, Alfranca A, Muñoz-Fernández MÁ, Buzón MJ, Martín-Gayo E. Calvet-Mirabent M, et al. EBioMedicine. 2022 Jul;81:104090. doi: 10.1016/j.ebiom.2022.104090. Epub 2022 Jun 2. EBioMedicine. 2022. PMID: 35665682 Free PMC article.
NLRC4-mediated activation of CD1c+ DC contributes to perpetuation of synovitis in rheumatoid arthritis.
Delgado-Arévalo C, Calvet-Mirabent M, Triguero-Martínez A, Vázquez de Luis E, Benguría-Filippini A, Largo R, Calzada-Fraile D, Popova O, Sánchez-Cerrillo I, Tsukalov I, Moreno-Vellisca R, de la Fuente H, Herrero-Beaumont G, Ramiro A, Sánchez-Madrid F, Castañeda S, Dopazo A, González Álvaro I, Martin-Gayo E. Delgado-Arévalo C, et al. Among authors: sanchez cerrillo i. JCI Insight. 2022 Nov 22;7(22):e152886. doi: 10.1172/jci.insight.152886. JCI Insight. 2022. PMID: 36194479 Free PMC article.
Effectiveness and tolerability of dolutegravir/lamivudine for the treatment of HIV-1 infection in clinical practice.
Suárez-García I, Alejos B, Hernando V, Viñuela L, Vera García M, Rial-Crestelo D, Pérez Elías MJ, Albendín Iglesias H, Peraire J, Tiraboschi J, Díaz A, Moreno S, Jarrín I; Cohort of the Spanish HIV/AIDS Research Network (CoRIS). Suárez-García I, et al. J Antimicrob Chemother. 2023 Jun 1;78(6):1423-1432. doi: 10.1093/jac/dkad102. J Antimicrob Chemother. 2023. PMID: 37099559 Free PMC article.
Occurrence of SARS-CoV-2 viremia is associated with genetic variants of genes related to COVID-19 pathogenesis.
Roy-Vallejo E, Fernández De Córdoba-Oñate S, Delgado-Wicke P, Triguero-Martínez A, Montes N, Carracedo-Rodríguez R, Zurita-Cruz N, Marcos-Jiménez A, Lamana A, Galván-Román JM, Villapalos García G, Zubiaur P, Ciudad M, Rabes L, Sanz M, Rodríguez C, Villa A, Rodríguez JÁ, Marcos C, Hernando J, Díaz-Fernández P, Abad F, de Los Santos I, Rodríguez Serrano DA, García-Vicuña R, Suárez Fernández C, P Gomariz R, Muñoz-Calleja C, Fernández-Ruiz E, González-Álvaro I, Cardeñoso L; PREDINMUN-COVID Group; Barrios A, Sanz J, Casado P, Gutiérrez Á, Bautista A, Hernández P, Ruiz Giménez N, Moyano B, Gil P, Jesús Delgado M, Parra P, Sánchez B, Sáez C, Fernández Rico M, Arévalo Román C, Castañeda S, Llorente I, G Tomero E, García Castañeda N, Uriarte M, Fontán García-Rodrigo L, Domingo García D, Alarcón Cavero T, Auxiliadora Semiglia Chong M, Gutiérrez Cobos A, Sánchez-Madrid F, Martín Gayo E, Sánchez-Cerrillo I, Martínez-Fleta P, López-Sanz C, Gabrie L, Del Campo Guerola L, Tejedor R, Ancochea J, García Castillo E, Ávalos E, Sánchez-Azofra A, Alonso T, Cisneros C, Valenzuela C, Javier García Pérez F, María Girón R, Aspa J, Marcos C, Del Perpetuo Socorro Churruca M, Zamora E, Martínez A, Bar… See abstract for full author list ➔ Roy-Vallejo E, et al. Among authors: sanchez cerrillo i. Front Med (Lausanne). 2023 Sep 22;10:1215246. doi: 10.3389/fmed.2023.1215246. eCollection 2023. Front Med (Lausanne). 2023. PMID: 37809329 Free PMC article.
Deregulated cellular circuits driving immunoglobulins and complement consumption associate with the severity of COVID-19 patients.
Marcos-Jiménez A, Sánchez-Alonso S, Alcaraz-Serna A, Esparcia L, López-Sanz C, Sampedro-Núñez M, Mateu-Albero T, Sánchez-Cerrillo I, Martínez-Fleta P, Gabrie L, Del Campo Guerola L, Rodríguez-Frade JM, Casasnovas JM, Reyburn HT, Valés-Gómez M, López-Trascasa M, Martín-Gayo E, Calzada MJ, Castañeda S, de la Fuente H, González-Álvaro I, Sánchez-Madrid F, Muñoz-Calleja C, Alfranca A. Marcos-Jiménez A, et al. Eur J Immunol. 2021 Mar;51(3):634-647. doi: 10.1002/eji.202048858. Epub 2021 Jan 22. Eur J Immunol. 2021. PMID: 33251605 Free PMC article.
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