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A transient protein folding response targets aggregation in the early phase of TDP-43-mediated neurodegeneration.
San Gil R, Pascovici D, Venturato J, Brown-Wright H, Mehta P, Madrid San Martin L, Wu J, Luan W, Chui YK, Bademosi AT, Swaminathan S, Naidoo S, Berning BA, Wright AL, Keating SS, Curtis MA, Faull RLM, Lee JD, Ngo ST, Lee A, Morsch M, Chung RS, Scotter E, Lisowski L, Mirzaei M, Walker AK. San Gil R, et al. Nat Commun. 2024 Feb 19;15(1):1508. doi: 10.1038/s41467-024-45646-9. Nat Commun. 2024. PMID: 38374041 Free PMC article.
Riluzole does not ameliorate disease caused by cytoplasmic TDP-43 in a mouse model of amyotrophic lateral sclerosis.
Wright AL, Della Gatta PA, Le S, Berning BA, Mehta P, Jacobs KR, Gul H, San Gil R, Hedl TJ, Riddell WR, Watson O, Keating SS, Venturato J, Chung RS, Atkin JD, Lee A, Shi B, Blizzard CA, Morsch M, Walker AK. Wright AL, et al. Among authors: san gil r. Eur J Neurosci. 2021 Sep;54(6):6237-6255. doi: 10.1111/ejn.15422. Epub 2021 Aug 26. Eur J Neurosci. 2021. PMID: 34390052
TDP-43 pathology: From noxious assembly to therapeutic removal.
Keating SS, San Gil R, Swanson MEV, Scotter EL, Walker AK. Keating SS, et al. Among authors: san gil r. Prog Neurobiol. 2022 Apr;211:102229. doi: 10.1016/j.pneurobio.2022.102229. Epub 2022 Jan 29. Prog Neurobiol. 2022. PMID: 35101542 Review.
UndERACting ion channels in neurodegeneration.
Jacobs MT, San Gil R, Walker AK. Jacobs MT, et al. Among authors: san gil r. Trends Neurosci. 2024 Feb;47(2):87-89. doi: 10.1016/j.tins.2023.11.002. Epub 2023 Nov 29. Trends Neurosci. 2024. PMID: 38030509
Proteomics Approaches for Biomarker and Drug Target Discovery in ALS and FTD.
Hedl TJ, San Gil R, Cheng F, Rayner SL, Davidson JM, De Luca A, Villalva MD, Ecroyd H, Walker AK, Lee A. Hedl TJ, et al. Among authors: san gil r. Front Neurosci. 2019 Jun 11;13:548. doi: 10.3389/fnins.2019.00548. eCollection 2019. Front Neurosci. 2019. PMID: 31244593 Free PMC article. Review.
24 results