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Page 1
Melanoma models for the next generation of therapies.
Patton EE, Mueller KL, Adams DJ, Anandasabapathy N, Aplin AE, Bertolotto C, Bosenberg M, Ceol CJ, Burd CE, Chi P, Herlyn M, Holmen SL, Karreth FA, Kaufman CK, Khan S, Kobold S, Leucci E, Levy C, Lombard DB, Lund AW, Marie KL, Marine JC, Marais R, McMahon M, Robles-Espinoza CD, Ronai ZA, Samuels Y, Soengas MS, Villanueva J, Weeraratna AT, White RM, Yeh I, Zhu J, Zon LI, Hurlbert MS, Merlino G. Patton EE, et al. Among authors: samuels y. Cancer Cell. 2021 May 10;39(5):610-631. doi: 10.1016/j.ccell.2021.01.011. Epub 2021 Feb 4. Cancer Cell. 2021. PMID: 33545064 Free PMC article. Review.
Mutant PIK3CA promotes cell growth and invasion of human cancer cells.
Samuels Y, Diaz LA Jr, Schmidt-Kittler O, Cummins JM, Delong L, Cheong I, Rago C, Huso DL, Lengauer C, Kinzler KW, Vogelstein B, Velculescu VE. Samuels Y, et al. Cancer Cell. 2005 Jun;7(6):561-73. doi: 10.1016/j.ccr.2005.05.014. Cancer Cell. 2005. PMID: 15950905 Free article.
Analysis of the matrix metalloproteinase family reveals that MMP8 is often mutated in melanoma.
Palavalli LH, Prickett TD, Wunderlich JR, Wei X, Burrell AS, Porter-Gill P, Davis S, Wang C, Cronin JC, Agrawal NS, Lin JC, Westbroek W, Hoogstraten-Miller S, Molinolo AA, Fetsch P, Filie AC, O'Connell MP, Banister CE, Howard JD, Buckhaults P, Weeraratna AT, Brody LC, Rosenberg SA, Samuels Y. Palavalli LH, et al. Among authors: samuels y. Nat Genet. 2009 May;41(5):518-20. doi: 10.1038/ng.340. Epub 2009 Mar 29. Nat Genet. 2009. PMID: 19330028 Free PMC article.
Frequent mutations in the MITF pathway in melanoma.
Cronin JC, Wunderlich J, Loftus SK, Prickett TD, Wei X, Ridd K, Vemula S, Burrell AS, Agrawal NS, Lin JC, Banister CE, Buckhaults P, Rosenberg SA, Bastian BC, Pavan WJ, Samuels Y. Cronin JC, et al. Among authors: samuels y. Pigment Cell Melanoma Res. 2009 Aug;22(4):435-44. doi: 10.1111/j.1755-148X.2009.00578.x. Epub 2009 Apr 29. Pigment Cell Melanoma Res. 2009. PMID: 19422606 Free PMC article.
Novel somatic mutations in heterotrimeric G proteins in melanoma.
Cárdenas-Navia LI, Cruz P, Lin JC; NISC Comparative Sequencing Program; Rosenberg SA, Samuels Y. Cárdenas-Navia LI, et al. Among authors: samuels y. Cancer Biol Ther. 2010 Jul 1;10(1):33-7. doi: 10.4161/cbt.10.1.11949. Cancer Biol Ther. 2010. PMID: 20424519 Free PMC article.
Delving into somatic variation in sporadic melanoma.
Walia V, Mu EW, Lin JC, Samuels Y. Walia V, et al. Among authors: samuels y. Pigment Cell Melanoma Res. 2012 Mar;25(2):155-70. doi: 10.1111/j.1755-148X.2012.00976.x. Epub 2012 Feb 13. Pigment Cell Melanoma Res. 2012. PMID: 22260482 Free PMC article. Review.
Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation.
Kim H, Frederick DT, Levesque MP, Cooper ZA, Feng Y, Krepler C, Brill L, Samuels Y, Hayward NK, Perlina A, Piris A, Zhang T, Halaban R, Herlyn MM, Brown KM, Wargo JA, Dummer R, Flaherty KT, Ronai ZA. Kim H, et al. Among authors: samuels y. Cell Rep. 2015 Jun 9;11(9):1458-73. doi: 10.1016/j.celrep.2015.04.049. Epub 2015 May 28. Cell Rep. 2015. PMID: 26027934 Free PMC article.
Extreme Vulnerability of IDH1 Mutant Cancers to NAD+ Depletion.
Tateishi K, Wakimoto H, Iafrate AJ, Tanaka S, Loebel F, Lelic N, Wiederschain D, Bedel O, Deng G, Zhang B, He T, Shi X, Gerszten RE, Zhang Y, Yeh JJ, Curry WT, Zhao D, Sundaram S, Nigim F, Koerner MVA, Ho Q, Fisher DE, Roider EM, Kemeny LV, Samuels Y, Flaherty KT, Batchelor TT, Chi AS, Cahill DP. Tateishi K, et al. Among authors: samuels y. Cancer Cell. 2015 Dec 14;28(6):773-784. doi: 10.1016/j.ccell.2015.11.006. Cancer Cell. 2015. PMID: 26678339 Free PMC article.
Parkin Somatic Mutations Link Melanoma and Parkinson's Disease.
Levin L, Srour S, Gartner J, Kapitansky O, Qutob N, Dror S, Golan T, Dayan R, Brener R, Ziv T, Khaled M, Schueler-Furman O, Samuels Y, Levy C. Levin L, et al. Among authors: samuels y. J Genet Genomics. 2016 Jun 20;43(6):369-79. doi: 10.1016/j.jgg.2016.05.005. Epub 2016 May 13. J Genet Genomics. 2016. PMID: 27297116
107 results