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Bispecific antibodies engage T cells for antitumor immunotherapy.
Choi BD, Cai M, Bigner DD, Mehta AI, Kuan CT, Sampson JH. Choi BD, et al. Among authors: sampson jh. Expert Opin Biol Ther. 2011 Jul;11(7):843-53. doi: 10.1517/14712598.2011.572874. Epub 2011 Mar 30. Expert Opin Biol Ther. 2011. PMID: 21449821 Review.
Monoclonal antibody blockade of IL-2 receptor α during lymphopenia selectively depletes regulatory T cells in mice and humans.
Mitchell DA, Cui X, Schmittling RJ, Sanchez-Perez L, Snyder DJ, Congdon KL, Archer GE, Desjardins A, Friedman AH, Friedman HS, Herndon JE 2nd, McLendon RE, Reardon DA, Vredenburgh JJ, Bigner DD, Sampson JH. Mitchell DA, et al. Among authors: sampson jh. Blood. 2011 Sep 15;118(11):3003-12. doi: 10.1182/blood-2011-02-334565. Epub 2011 Jul 18. Blood. 2011. PMID: 21768296 Free PMC article. Clinical Trial.
Enzyme redesign guided by cancer-derived IDH1 mutations.
Reitman ZJ, Choi BD, Spasojevic I, Bigner DD, Sampson JH, Yan H. Reitman ZJ, et al. Among authors: sampson jh. Nat Chem Biol. 2012 Nov;8(11):887-9. doi: 10.1038/nchembio.1065. Epub 2012 Sep 23. Nat Chem Biol. 2012. PMID: 23001033 Free PMC article.
331 results