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The anti-obesity effect of FGF19 does not require UCP1-dependent thermogenesis.
Antonellis PJ, Droz BA, Cosgrove R, O'Farrell LS, Coskun T, Perfield JW 2nd, Bauer S, Wade M, Chouinard TE, Brozinick JT, Adams AC, Samms RJ. Antonellis PJ, et al. Among authors: samms rj. Mol Metab. 2019 Dec;30:131-139. doi: 10.1016/j.molmet.2019.09.006. Epub 2019 Sep 29. Mol Metab. 2019. PMID: 31767164 Free PMC article.
Whole-body and adipose tissue-specific mechanisms underlying the metabolic effects of fibroblast growth factor 21 in the Siberian hamster.
Lewis JE, Monnier C, Marshall H, Fowler M, Green R, Cooper S, Chiotellis A, Luckett J, Perkins AC, Coskun T, Adams AC, Samms RJ, Ebling FJP, Tsintzas K. Lewis JE, et al. Among authors: samms rj. Mol Metab. 2020 Jan;31:45-54. doi: 10.1016/j.molmet.2019.10.009. Epub 2019 Nov 9. Mol Metab. 2020. PMID: 31918921 Free PMC article.
GIPR agonism mediates weight-independent insulin sensitization by tirzepatide in obese mice.
Samms RJ, Christe ME, Collins KA, Pirro V, Droz BA, Holland AK, Friedrich JL, Wojnicki S, Konkol DL, Cosgrove R, Furber EPC, Ruan X, O'Farrell LS, Long AM, Dogra M, Willency JA, Lin Y, Ding L, Cheng CC, Cabrera O, Briere DA, Alsina-Fernandez J, Gimeno RE, Moyers JS, Coskun T, Coghlan MP, Sloop KW, Roell WC. Samms RJ, et al. J Clin Invest. 2021 Jun 15;131(12):e146353. doi: 10.1172/JCI146353. J Clin Invest. 2021. PMID: 34003802 Free PMC article.
GIP Receptor Agonism Attenuates GLP-1 Receptor Agonist-Induced Nausea and Emesis in Preclinical Models.
Borner T, Geisler CE, Fortin SM, Cosgrove R, Alsina-Fernandez J, Dogra M, Doebley S, Sanchez-Navarro MJ, Leon RM, Gaisinsky J, White A, Bamezai A, Ghidewon MY, Grill HJ, Crist RC, Reiner BC, Ai M, Samms RJ, De Jonghe BC, Hayes MR. Borner T, et al. Among authors: samms rj. Diabetes. 2021 Nov;70(11):2545-2553. doi: 10.2337/db21-0459. Epub 2021 Aug 11. Diabetes. 2021. PMID: 34380697 Free PMC article.
GIPR Agonism Inhibits PYY-Induced Nausea-Like Behavior.
Samms RJ, Cosgrove R, Snider BM, Furber EC, Droz BA, Briere DA, Dunbar J, Dogra M, Alsina-Fernandez J, Borner T, De Jonghe BC, Hayes MR, Coskun T, Sloop KW, Emmerson PJ, Ai M. Samms RJ, et al. Diabetes. 2022 Jul 1;71(7):1410-1423. doi: 10.2337/db21-0848. Diabetes. 2022. PMID: 35499381 Free PMC article.
Is Glucagon Receptor Activation the Thermogenic Solution for Treating Obesity?
Conceição-Furber E, Coskun T, Sloop KW, Samms RJ. Conceição-Furber E, et al. Among authors: samms rj. Front Endocrinol (Lausanne). 2022 Apr 25;13:868037. doi: 10.3389/fendo.2022.868037. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 35547006 Free PMC article. Review.
30 results