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Mechanisms of simvastatin myotoxicity: The role of autophagy flux inhibition.
Emami A, Shojaei S, da Silva Rosa SC, Aghaei M, Samiei E, Vosoughi AR, Kalantari F, Kawalec P, Thliveris J, Sharma P, Zeki AA, Akbari M, Gordon JW, Ghavami S. Emami A, et al. Among authors: samiei e. Eur J Pharmacol. 2019 Nov 5;862:172616. doi: 10.1016/j.ejphar.2019.172616. Epub 2019 Aug 23. Eur J Pharmacol. 2019. PMID: 31449810
Simvastatin increases temozolomide-induced cell death by targeting the fusion of autophagosomes and lysosomes.
Shojaei S, Koleini N, Samiei E, Aghaei M, Cole LK, Alizadeh J, Islam MI, Vosoughi AR, Albokashy M, Butterfield Y, Marzban H, Xu F, Thliveris J, Kardami E, Hatch GM, Eftekharpour E, Akbari M, Hombach-Klonisch S, Klonisch T, Ghavami S. Shojaei S, et al. Among authors: samiei e. FEBS J. 2020 Mar;287(5):1005-1034. doi: 10.1111/febs.15069. Epub 2019 Oct 14. FEBS J. 2020. PMID: 31545550 Free article.
23 results