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The Antifungal Itraconazole Is a Potent Inhibitor of Chikungunya Virus Replication.
Policastro LR, Dolci I, Godoy AS, Silva Júnior JVJ, Ruiz UEA, Santos IA, Jardim ACG, Samby K, Burrows JN, Wells TNC, Gil LHVG, Oliva G, Fernandes RS. Policastro LR, et al. Among authors: samby k. Viruses. 2022 Jun 21;14(7):1351. doi: 10.3390/v14071351. Viruses. 2022. PMID: 35891332 Free PMC article.
Partnering to fight malaria in India: Past, present and future.
Samby K, Ramachandruni H, Banerji J, Burrows JN, Daumerie PG, Hooft van Huijsduijnen RAM, Duparc S, Wells TNC. Samby K, et al. J Vector Borne Dis. 2019 Jan-Mar;56(1):15-24. doi: 10.4103/0972-9062.257769. J Vector Borne Dis. 2019. PMID: 31070161 Review.
Actives from MMV Open Access Boxes? A suggested way forward.
Samby K, Willis PA, Burrows JN, Laleu B, Webborn PJH. Samby K, et al. PLoS Pathog. 2021 Apr 22;17(4):e1009384. doi: 10.1371/journal.ppat.1009384. eCollection 2021 Apr. PLoS Pathog. 2021. PMID: 33886696 Free PMC article. Review.
Molnupiravir combined with different repurposed drugs further inhibits SARS-CoV-2 infection in human nasal epithelium in vitro.
Jonsdottir HR, Siegrist D, Julien T, Padey B, Bouveret M, Terrier O, Pizzorno A, Huang S, Samby K, Wells TNC, Boda B, Rosa-Calatrava M, Engler OB, Constant S. Jonsdottir HR, et al. Among authors: samby k. Biomed Pharmacother. 2022 Jun;150:113058. doi: 10.1016/j.biopha.2022.113058. Epub 2022 May 2. Biomed Pharmacother. 2022. PMID: 35658229 Free PMC article.
The Pandemic Response Box─Accelerating Drug Discovery Efforts after Disease Outbreaks.
Samby K, Besson D, Dutta A, Patra B, Doy A, Glossop P, Mills J, Whitlock G, Hooft van Huijsduijnen R, Monaco A, Bilbe G, Mowbray C, Perry B, Adam A, Wells TNC, Willis PA. Samby K, et al. ACS Infect Dis. 2022 Apr 8;8(4):713-720. doi: 10.1021/acsinfecdis.1c00527. Epub 2022 Mar 14. ACS Infect Dis. 2022. PMID: 35286809 Free PMC article.
Screening the pandemic response box identified benzimidazole carbamates, Olorofim and ravuconazole as promising drug candidates for the treatment of eumycetoma.
Lim W, Nyuykonge B, Eadie K, Konings M, Smeets J, Fahal A, Bonifaz A, Todd M, Perry B, Samby K, Burrows J, Verbon A, van de Sande W. Lim W, et al. Among authors: samby k. PLoS Negl Trop Dis. 2022 Feb 4;16(2):e0010159. doi: 10.1371/journal.pntd.0010159. eCollection 2022 Feb. PLoS Negl Trop Dis. 2022. PMID: 35120131 Free PMC article.
'Erythritol', a safe natural sweetener exhibits multi-stage anti-malarial activity by permeating into Plasmodium falciparum through aquaglyceroporin channel.
Kumari J, Kumar V, Behl A, Kumar Sah R, Kumari G, Garg S, Gupta A, Nazar Mohomed Mohaideen S, Shafi S, Pati S, Samby K, Burrows J, Mohandas N, Singh S. Kumari J, et al. Among authors: samby k. Biochem Pharmacol. 2022 Nov;205:115287. doi: 10.1016/j.bcp.2022.115287. Epub 2022 Oct 6. Biochem Pharmacol. 2022. PMID: 36209839
Screening of the Pandemic Response Box Reveals an Association between Antifungal Effects of MMV1593537 and the Cell Wall of Cryptococcus neoformans, Cryptococcus deuterogattii, and Candida auris.
de Oliveira HC, Castelli RF, Reis FCG, Samby K, Nosanchuk JD, Alves LR, Rodrigues ML. de Oliveira HC, et al. Among authors: samby k. Microbiol Spectr. 2022 Jun 29;10(3):e0060122. doi: 10.1128/spectrum.00601-22. Epub 2022 Apr 26. Microbiol Spectr. 2022. PMID: 35471056 Free PMC article.
15 results