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Fumarate induces vesicular release of mtDNA to drive innate immunity.
Zecchini V, Paupe V, Herranz-Montoya I, Janssen J, Wortel IMN, Morris JL, Ferguson A, Chowdury SR, Segarra-Mondejar M, Costa ASH, Pereira GC, Tronci L, Young T, Nikitopoulou E, Yang M, Bihary D, Caicci F, Nagashima S, Speed A, Bokea K, Baig Z, Samarajiwa S, Tran M, Mitchell T, Johnson M, Prudent J, Frezza C. Zecchini V, et al. Among authors: samarajiwa s. Nature. 2023 Mar;615(7952):499-506. doi: 10.1038/s41586-023-05770-w. Epub 2023 Mar 8. Nature. 2023. PMID: 36890229 Free PMC article.
Systems biology of interferon responses.
Hertzog P, Forster S, Samarajiwa S. Hertzog P, et al. Among authors: samarajiwa s. J Interferon Cytokine Res. 2011 Jan;31(1):5-11. doi: 10.1089/jir.2010.0126. J Interferon Cytokine Res. 2011. PMID: 21226606 Review.
INTERFEROME: the database of interferon regulated genes.
Samarajiwa SA, Forster S, Auchettl K, Hertzog PJ. Samarajiwa SA, et al. Nucleic Acids Res. 2009 Jan;37(Database issue):D852-7. doi: 10.1093/nar/gkn732. Epub 2008 Nov 7. Nucleic Acids Res. 2009. PMID: 18996892 Free PMC article.
Spatial coupling of mTOR and autophagy augments secretory phenotypes.
Narita M, Young AR, Arakawa S, Samarajiwa SA, Nakashima T, Yoshida S, Hong S, Berry LS, Reichelt S, Ferreira M, Tavaré S, Inoki K, Shimizu S, Narita M. Narita M, et al. Among authors: samarajiwa sa. Science. 2011 May 20;332(6032):966-70. doi: 10.1126/science.1205407. Epub 2011 Apr 21. Science. 2011. PMID: 21512002 Free PMC article.
HIV infection of dendritic cells subverts the IFN induction pathway via IRF-1 and inhibits type 1 IFN production.
Harman AN, Lai J, Turville S, Samarajiwa S, Gray L, Marsden V, Mercier SK, Jones K, Nasr N, Rustagi A, Cumming H, Donaghy H, Mak J, Gale M Jr, Churchill M, Hertzog P, Cunningham AL. Harman AN, et al. Among authors: samarajiwa s. Blood. 2011 Jul 14;118(2):298-308. doi: 10.1182/blood-2010-07-297721. Epub 2011 Mar 16. Blood. 2011. PMID: 21411754 Free PMC article.
NOTCH-mediated non-cell autonomous regulation of chromatin structure during senescence.
Parry AJ, Hoare M, Bihary D, Hänsel-Hertsch R, Smith S, Tomimatsu K, Mannion E, Smith A, D'Santos P, Russell IA, Balasubramanian S, Kimura H, Samarajiwa SA, Narita M. Parry AJ, et al. Among authors: samarajiwa sa. Nat Commun. 2018 May 9;9(1):1840. doi: 10.1038/s41467-018-04283-9. Nat Commun. 2018. PMID: 29743479 Free PMC article.
29 results