Salvemini D - Search Results

1

Uncovering the Mechanisms of Adenosine Receptor-Mediated Pain Control: Focus on the A₃ Receptor Subtype.

Coppi E, Cherchi F, Lucarini E, Ghelardini C, Pedata F, Jacobson KA, Di Cesare Mannelli L, Pugliese AM, Salvemini D. Coppi E, et al. Among authors: salvemini d. Int J Mol Sci. 2021 Jul 26;22(15):7952. doi: 10.3390/ijms22157952. Int J Mol Sci. 2021. PMID: 34360719 Free PMC article. Review.

2

Controlling murine and rat chronic pain through A3 adenosine receptor activation.

Chen Z, Janes K, Chen C, Doyle T, Bryant L, Tosh DK, Jacobson KA, Salvemini D. Chen Z, et al. Among authors: salvemini d. FASEB J. 2012 May;26(5):1855-65. doi: 10.1096/fj.11-201541. Epub 2012 Feb 17. FASEB J. 2012. PMID: 22345405 Free PMC article.

3

Rational design of sulfonated A3 adenosine receptor-selective nucleosides as pharmacological tools to study chronic neuropathic pain.

Paoletta S, Tosh DK, Finley A, Gizewski ET, Moss SM, Gao ZG, Auchampach JA, Salvemini D, Jacobson KA. Paoletta S, et al. Among authors: salvemini d. J Med Chem. 2013 Jul 25;56(14):5949-63. doi: 10.1021/jm4007966. Epub 2013 Jul 3. J Med Chem. 2013. PMID: 23789857 Free PMC article.

4

Structural probing of off-target G protein-coupled receptor activities within a series of adenosine/adenine congeners.

Paoletta S, Tosh DK, Salvemini D, Jacobson KA. Paoletta S, et al. Among authors: salvemini d. PLoS One. 2014 May 23;9(5):e97858. doi: 10.1371/journal.pone.0097858. eCollection 2014. PLoS One. 2014. PMID: 24859150 Free PMC article.

5

Extended N(6) substitution of rigid C2-arylethynyl nucleosides for exploring the role of extracellular loops in ligand recognition at the A3 adenosine receptor.

Tosh DK, Paoletta S, Chen Z, Moss SM, Gao ZG, Salvemini D, Jacobson KA. Tosh DK, et al. Among authors: salvemini d. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3302-6. doi: 10.1016/j.bmcl.2014.06.006. Epub 2014 Jun 11. Bioorg Med Chem Lett. 2014. PMID: 24969016 Free PMC article.

6

Spinal neuroimmune activation is independent of T-cell infiltration and attenuated by A3 adenosine receptor agonists in a model of oxaliplatin-induced peripheral neuropathy.

Janes K, Wahlman C, Little JW, Doyle T, Tosh DK, Jacobson KA, Salvemini D. Janes K, et al. Among authors: salvemini d. Brain Behav Immun. 2015 Feb;44:91-9. doi: 10.1016/j.bbi.2014.08.010. Epub 2014 Sep 8. Brain Behav Immun. 2015. PMID: 25220279 Free PMC article.

7

A3 adenosine receptor agonist prevents the development of paclitaxel-induced neuropathic pain by modulating spinal glial-restricted redox-dependent signaling pathways.

Janes K, Esposito E, Doyle T, Cuzzocrea S, Tosh DK, Jacobson KA, Salvemini D. Janes K, et al. Among authors: salvemini d. Pain. 2014 Dec;155(12):2560-2567. doi: 10.1016/j.pain.2014.09.016. Epub 2014 Sep 19. Pain. 2014. PMID: 25242567 Free PMC article.

8

Endogenous adenosine A3 receptor activation selectively alleviates persistent pain states.

Little JW, Ford A, Symons-Liguori AM, Chen Z, Janes K, Doyle T, Xie J, Luongo L, Tosh DK, Maione S, Bannister K, Dickenson AH, Vanderah TW, Porreca F, Jacobson KA, Salvemini D. Little JW, et al. Among authors: salvemini d. Brain. 2015 Jan;138(Pt 1):28-35. doi: 10.1093/brain/awu330. Epub 2014 Nov 19. Brain. 2015. PMID: 25414036 Free PMC article.

9

In vivo phenotypic screening for treating chronic neuropathic pain: modification of C2-arylethynyl group of conformationally constrained A3 adenosine receptor agonists.

Tosh DK, Finley A, Paoletta S, Moss SM, Gao ZG, Gizewski ET, Auchampach JA, Salvemini D, Jacobson KA. Tosh DK, et al. Among authors: salvemini d. J Med Chem. 2014 Dec 11;57(23):9901-14. doi: 10.1021/jm501021n. Epub 2014 Nov 25. J Med Chem. 2014. PMID: 25422861 Free PMC article.

10

Engagement of the GABA to KCC2 signaling pathway contributes to the analgesic effects of A3AR agonists in neuropathic pain.

Ford A, Castonguay A, Cottet M, Little JW, Chen Z, Symons-Liguori AM, Doyle T, Egan TM, Vanderah TW, De Koninck Y, Tosh DK, Jacobson KA, Salvemini D. Ford A, et al. Among authors: salvemini d. J Neurosci. 2015 Apr 15;35(15):6057-67. doi: 10.1523/JNEUROSCI.4495-14.2015. J Neurosci. 2015. PMID: 25878279 Free PMC article.

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