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Small molecule nitroalkenes inhibit RAD51-mediated homologous recombination and amplify triple-negative breast cancer cell killing by DNA-directed therapies.
Hong L, Braden DC, Zhao Y, Skoko JJ, Chang F, Woodcock SR, Uvalle C, Casey A, Wood K, Salvatore SR, Asan A, Harkness T, Fagunloye A, Razzaghi M, Straub A, Spies M, Brown DD, Lee AV, Schopfer F, Freeman BA, Neumann CA. Hong L, et al. Among authors: salvatore sr. bioRxiv [Preprint]. 2023 Aug 14:2023.08.11.552990. doi: 10.1101/2023.08.11.552990. bioRxiv. 2023. PMID: 37645906 Free PMC article. Updated. Preprint.
Small molecule nitroalkenes inhibit RAD51-mediated homologous recombination and amplify triple-negative breast cancer cell killing by DNA-directed therapies.
Hong L, Braden DC, Zhao Y, Skoko JJ, Chang F, Woodcock SR, Uvalle C, Casey A, Wood K, Salvatore SR, Asan A, Harkness T, Fagunloye A, Razzaghi M, Straub A, Spies M, Brown DD, Lee AV, Schopfer F, Freeman BA, Neumann CA. Hong L, et al. Among authors: salvatore sr. Redox Biol. 2023 Oct;66:102856. doi: 10.1016/j.redox.2023.102856. Epub 2023 Aug 19. Redox Biol. 2023. PMID: 37633047 Free PMC article.
Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase.
Hicks KG, Cluntun AA, Schubert HL, Hackett SR, Berg JA, Leonard PG, Ajalla Aleixo MA, Zhou Y, Bott AJ, Salvatore SR, Chang F, Blevins A, Barta P, Tilley S, Leifer A, Guzman A, Arok A, Fogarty S, Winter JM, Ahn HC, Allen KN, Block S, Cardoso IA, Ding J, Dreveny I, Gasper WC, Ho Q, Matsuura A, Palladino MJ, Prajapati S, Sun P, Tittmann K, Tolan DR, Unterlass J, VanDemark AP, Vander Heiden MG, Webb BA, Yun CH, Zhao P, Wang B, Schopfer FJ, Hill CP, Nonato MC, Muller FL, Cox JE, Rutter J. Hicks KG, et al. Among authors: salvatore sr. Science. 2023 Mar 10;379(6636):996-1003. doi: 10.1126/science.abm3452. Epub 2023 Mar 9. Science. 2023. PMID: 36893255 Free PMC article.
CYB5R3 in type II alveolar epithelial cells protects against lung fibrosis by suppressing TGF-β1 signaling.
Bueno M, Calyeca J, Khaliullin T, Miller MP, Alvarez D, Rosas L, Brands J, Baker C, Nasser A, Shulkowski S, Mathien A, Uzoukwu N, Sembrat J, Mays BG, Fiedler K, Hahn SA, Salvatore SR, Schopfer FJ, Rojas M, Sandner P, Straub AC, Mora AL. Bueno M, et al. Among authors: salvatore sr. JCI Insight. 2023 Mar 8;8(5):e161487. doi: 10.1172/jci.insight.161487. JCI Insight. 2023. PMID: 36749633 Free PMC article.
Immunomodulatory actions of a kynurenine-derived endogenous electrophile.
Carreño M, Pires MF, Woodcock SR, Brzoska T, Ghosh S, Salvatore SR, Chang F, Khoo NKH, Dunn M, Connors N, Yuan S, Straub AC, Wendell SG, Kato GJ, Freeman BA, Ofori-Acquah SF, Sundd P, Schopfer FJ, Vitturi DA. Carreño M, et al. Among authors: salvatore sr. Sci Adv. 2022 Jul;8(26):eabm9138. doi: 10.1126/sciadv.abm9138. Epub 2022 Jun 29. Sci Adv. 2022. PMID: 35767602 Free PMC article.
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