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Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effect.
Salvati E, Leonetti C, Rizzo A, Scarsella M, Mottolese M, Galati R, Sperduti I, Stevens MF, D'Incalci M, Blasco M, Chiorino G, Bauwens S, Horard B, Gilson E, Stoppacciaro A, Zupi G, Biroccio A. Salvati E, et al. J Clin Invest. 2007 Nov;117(11):3236-47. doi: 10.1172/JCI32461. J Clin Invest. 2007. PMID: 17932567 Free PMC article.
SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage.
Rizzo A, Iachettini S, Salvati E, Zizza P, Maresca C, D'Angelo C, Benarroch-Popivker D, Capolupo A, Del Gaudio F, Cosconati S, Di Maro S, Merlino F, Novellino E, Amoreo CA, Mottolese M, Sperduti I, Gilson E, Biroccio A. Rizzo A, et al. Among authors: salvati e. Nucleic Acids Res. 2017 Feb 28;45(4):1820-1834. doi: 10.1093/nar/gkw1202. Nucleic Acids Res. 2017. PMID: 27923994 Free PMC article.
570 results