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The BACE1 product sAPPβ induces ER stress and inflammation and impairs insulin signaling.
Botteri G, Salvadó L, Gumà A, Lee Hamilton D, Meakin PJ, Montagut G, Ashford MLJ, Ceperuelo-Mallafré V, Fernández-Veledo S, Vendrell J, Calderón-Dominguez M, Serra D, Herrero L, Pizarro J, Barroso E, Palomer X, Vázquez-Carrera M. Botteri G, et al. Among authors: salvado l. Metabolism. 2018 Aug;85:59-75. doi: 10.1016/j.metabol.2018.03.005. Epub 2018 Mar 9. Metabolism. 2018. PMID: 29526536 Free article.
Targeting endoplasmic reticulum stress in insulin resistance.
Salvadó L, Palomer X, Barroso E, Vázquez-Carrera M. Salvadó L, et al. Trends Endocrinol Metab. 2015 Aug;26(8):438-48. doi: 10.1016/j.tem.2015.05.007. Epub 2015 Jun 12. Trends Endocrinol Metab. 2015. PMID: 26078196 Review.
Corrigendum to "The BACE1 product sAPPβ induces ER stress and inflammation and impairs insulin signaling" [Metab Clin Exp 85 (2018) 59-75].
Botteri G, Salvadó L, Gumà A, Hamilton DL, Meakin PJ, Montagut G, Ashford MLJ, Ceperuelo-Mallafré V, Fernández-Veledo S, Vendrell J, Calderón-Dominguez M, Serra D, Herrero L, Pizarro J, Barroso E, Palomer X, Vázquez-Carrera M. Botteri G, et al. Among authors: salvado l. Metabolism. 2019 Jul;96:101-102. doi: 10.1016/j.metabol.2019.04.009. Epub 2019 Apr 18. Metabolism. 2019. PMID: 31005247 No abstract available.
Targeting PPARβ/δ for the treatment of type 2 diabetes mellitus.
Salvadó L, Serrano-Marco L, Barroso E, Palomer X, Vázquez-Carrera M. Salvadó L, et al. Expert Opin Ther Targets. 2012 Feb;16(2):209-23. doi: 10.1517/14728222.2012.658370. Epub 2012 Jan 27. Expert Opin Ther Targets. 2012. PMID: 22280315 Review.
TNF-α inhibits PPARβ/δ activity and SIRT1 expression through NF-κB in human adipocytes.
Serrano-Marco L, Chacón MR, Maymó-Masip E, Barroso E, Salvadó L, Wabitsch M, Garrido-Sánchez L, Tinahones FJ, Palomer X, Vendrell J, Vázquez-Carrera M. Serrano-Marco L, et al. Among authors: salvado l. Biochim Biophys Acta. 2012 Sep;1821(9):1177-85. doi: 10.1016/j.bbalip.2012.05.006. Epub 2012 Jun 7. Biochim Biophys Acta. 2012. PMID: 22683888 Clinical Trial.
Tau hyperphosphorylation and increased BACE1 and RAGE levels in the cortex of PPARβ/δ-null mice.
Barroso E, del Valle J, Porquet D, Vieira Santos AM, Salvadó L, Rodríguez-Rodríguez R, Gutiérrez P, Anglada-Huguet M, Alberch J, Camins A, Palomer X, Pallàs M, Michalik L, Wahli W, Vázquez-Carrera M. Barroso E, et al. Among authors: salvado l. Biochim Biophys Acta. 2013 Aug;1832(8):1241-8. doi: 10.1016/j.bbadis.2013.03.006. Epub 2013 Mar 16. Biochim Biophys Acta. 2013. PMID: 23507144 Free article.
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