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Small Molecule-Based Enzyme Inhibitors in the Treatment of Primary Hyperoxalurias.
Moya-Garzon MD, Gomez-Vidal JA, Alejo-Armijo A, Altarejos J, Rodriguez-Madoz JR, Fernandes MX, Salido E, Salido S, Diaz-Gavilan M. Moya-Garzon MD, et al. Among authors: salido s, salido e. J Pers Med. 2021 Jan 27;11(2):74. doi: 10.3390/jpm11020074. J Pers Med. 2021. PMID: 33513899 Free PMC article. Review.
New salicylic acid derivatives, double inhibitors of glycolate oxidase and lactate dehydrogenase, as effective agents decreasing oxalate production.
Moya-Garzon MD, Rodriguez-Rodriguez B, Martin-Higueras C, Franco-Montalban F, Fernandes MX, Gomez-Vidal JA, Pey AL, Salido E, Diaz-Gavilan M. Moya-Garzon MD, et al. Among authors: salido e. Eur J Med Chem. 2022 Jul 5;237:114396. doi: 10.1016/j.ejmech.2022.114396. Epub 2022 Apr 25. Eur J Med Chem. 2022. PMID: 35500475 Free article.
Primary hyperoxalurias: disorders of glyoxylate detoxification.
Salido E, Pey AL, Rodriguez R, Lorenzo V. Salido E, et al. Biochim Biophys Acta. 2012 Sep;1822(9):1453-64. doi: 10.1016/j.bbadis.2012.03.004. Epub 2012 Mar 14. Biochim Biophys Acta. 2012. PMID: 22446032 Free article. Review.
Specific Inhibition of Hepatic Lactate Dehydrogenase Reduces Oxalate Production in Mouse Models of Primary Hyperoxaluria.
Lai C, Pursell N, Gierut J, Saxena U, Zhou W, Dills M, Diwanji R, Dutta C, Koser M, Nazef N, Storr R, Kim B, Martin-Higueras C, Salido E, Wang W, Abrams M, Dudek H, Brown BD. Lai C, et al. Among authors: salido e. Mol Ther. 2018 Aug 1;26(8):1983-1995. doi: 10.1016/j.ymthe.2018.05.016. Epub 2018 Jun 15. Mol Ther. 2018. PMID: 29914758 Free PMC article.
Molecular therapy of primary hyperoxaluria.
Martin-Higueras C, Torres A, Salido E. Martin-Higueras C, et al. Among authors: salido e. J Inherit Metab Dis. 2017 Jul;40(4):481-489. doi: 10.1007/s10545-017-0045-3. Epub 2017 Apr 19. J Inherit Metab Dis. 2017. PMID: 28425073 Review.
Structural and functional insights on the roles of molecular chaperones in the mistargeting and aggregation phenotypes associated with primary hyperoxaluria type I.
Fernández-Higuero JÁ, Betancor-Fernández I, Mesa-Torres N, Muga A, Salido E, Pey AL. Fernández-Higuero JÁ, et al. Among authors: salido e. Adv Protein Chem Struct Biol. 2019;114:119-152. doi: 10.1016/bs.apcsb.2018.09.003. Epub 2018 Nov 28. Adv Protein Chem Struct Biol. 2019. PMID: 30635080 Review.
261 results