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A functional genomic framework to elucidate novel causal non-alcoholic fatty liver disease genes.
Saliba-Gustafsson P, Justesen JM, Ranta A, Sharma D, Bielczyk-Maczynska E, Li J, Najmi LA, Apodaka M, Aspichueta P, Björck HM, Eriksson P, Franco-Cereceda A, Gloudemans M, Mujica E, den Hoed M, Assimes TL, Quertermous T, Carcamo-Orive I, Park CY, Knowles JW. Saliba-Gustafsson P, et al. medRxiv [Preprint]. 2024 Feb 4:2024.02.03.24302258. doi: 10.1101/2024.02.03.24302258. medRxiv. 2024. PMID: 38352379 Free PMC article. Preprint.
A single-cell CRISPRi platform for characterizing candidate genes relevant to metabolic disorders in human adipocytes.
Bielczyk-Maczynska E, Sharma D, Blencowe M, Saliba Gustafsson P, Gloudemans MJ, Yang X, Carcamo-Orive I, Wabitsch M, Svensson KJ, Park CY, Quertermous T, Knowles JW, Li J. Bielczyk-Maczynska E, et al. Among authors: saliba gustafsson p. Am J Physiol Cell Physiol. 2023 Sep 1;325(3):C648-C660. doi: 10.1152/ajpcell.00148.2023. Epub 2023 Jul 24. Am J Physiol Cell Physiol. 2023. PMID: 37486064 Free article.
The tyrosine kinase inhibitor nilotinib targets the discoidin domain receptor DDR2 in calcific aortic valve stenosis.
Carracedo M, Pawelzik SC, Artiach G, Pouwer MG, Plunde O, Saliba-Gustafsson P, Ehrenborg E, Eriksson P, Pieterman E, Stenke L, Princen HMG, Franco-Cereceda A, Bäck M. Carracedo M, et al. Among authors: saliba gustafsson p. Br J Pharmacol. 2022 Oct;179(19):4709-4721. doi: 10.1111/bph.15911. Epub 2022 Jul 19. Br J Pharmacol. 2022. PMID: 35751904 Free PMC article.
Plaque Evaluation by Ultrasound and Transcriptomics Reveals BCLAF1 as a Regulator of Smooth Muscle Cell Lipid Transdifferentiation in Atherosclerosis.
Rykaczewska U, Zhao Q, Saliba-Gustafsson P, Lengquist M, Kronqvist M, Bergman O, Huang Z, Lund K, Waden K, Pons Vila Z, Caidahl K, Skogsberg J, Vukojevic V, Lindeman JHN, Roy J, Hansson GK, Treuter E, Leeper NJ, Eriksson P, Ehrenborg E, Razuvaev A, Hedin U, Matic L. Rykaczewska U, et al. Among authors: saliba gustafsson p. Arterioscler Thromb Vasc Biol. 2022 May;42(5):659-676. doi: 10.1161/ATVBAHA.121.317018. Epub 2022 Mar 24. Arterioscler Thromb Vasc Biol. 2022. PMID: 35321563 Free article.
Interactions of physical activity, muscular fitness, adiposity, and genetic risk for NAFLD.
Schnurr TM, Katz SF, Justesen JM, O'Sullivan JW, Saliba-Gustafsson P, Assimes TL, Carcamo-Orive I, Ahmed A, Ashley EA, Hansen T, Knowles JW. Schnurr TM, et al. Among authors: saliba gustafsson p. Hepatol Commun. 2022 Jul;6(7):1516-1526. doi: 10.1002/hep4.1932. Epub 2022 Mar 15. Hepatol Commun. 2022. PMID: 35293152 Free PMC article.
Subclinical atherosclerosis and its progression are modulated by PLIN2 through a feed-forward loop between LXR and autophagy.
Saliba-Gustafsson P, Pedrelli M, Gertow K, Werngren O, Janas V, Pourteymour S, Baldassarre D, Tremoli E, Veglia F, Rauramaa R, Smit AJ, Giral P, Kurl S, Pirro M, de Faire U, Humphries SE, Hamsten A; IMPROVE Study Group; Gonçalves I, Orho-Melander M, Franco-Cereceda A, Borén J, Eriksson P, Magné J, Parini P, Ehrenborg E. Saliba-Gustafsson P, et al. J Intern Med. 2019 Dec;286(6):660-675. doi: 10.1111/joim.12951. Epub 2019 Jul 29. J Intern Med. 2019. PMID: 31251843 Free PMC article.
Local Delivery of miR-21 Stabilizes Fibrous Caps in Vulnerable Atherosclerotic Lesions.
Jin H, Li DY, Chernogubova E, Sun C, Busch A, Eken SM, Saliba-Gustafsson P, Winter H, Winski G, Raaz U, Schellinger IN, Simon N, Hegenloh R, Matic LP, Jagodic M, Ehrenborg E, Pelisek J, Eckstein HH, Hedin U, Backlund A, Maegdefessel L. Jin H, et al. Among authors: saliba gustafsson p. Mol Ther. 2018 Apr 4;26(4):1040-1055. doi: 10.1016/j.ymthe.2018.01.011. Epub 2018 Jan 31. Mol Ther. 2018. PMID: 29503197 Free PMC article.
11 results