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An optogenetic method for the controlled release of single molecules.
Nat Methods. 2024 Apr;21(4):666-672. doi: 10.1038/s41592-024-02204-x. Epub 2024 Mar 8.
Nat Methods. 2024.
PMID: 38459384
Free PMC article.
Disulfide bridge-dependent dimerization triggers FGF2 membrane translocation into the extracellular space.
Lolicato F, Steringer JP, Saleppico R, Beyer D, Fernandez-Sobaberas J, Unger S, Klein S, Riegerová P, Wegehingel S, Müller HM, Schmitt XJ, Kaptan S, Freund C, Hof M, Šachl R, Chlanda P, Vattulainen I, Nickel W.
Lolicato F, et al. Among authors: saleppico r.
Elife. 2024 Jan 22;12:RP88579. doi: 10.7554/eLife.88579.
Elife. 2024.
PMID: 38252473
Free PMC article.
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Cholesterol promotes clustering of PI(4,5)P2 driving unconventional secretion of FGF2.
Lolicato F, Saleppico R, Griffo A, Meyer A, Scollo F, Pokrandt B, Müller HM, Ewers H, Hähl H, Fleury JB, Seemann R, Hof M, Brügger B, Jacobs K, Vattulainen I, Nickel W.
Lolicato F, et al. Among authors: saleppico r.
J Cell Biol. 2022 Nov 7;221(11):e202106123. doi: 10.1083/jcb.202106123. Epub 2022 Sep 29.
J Cell Biol. 2022.
PMID: 36173379
Free PMC article.
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Unconventional secretion mediated by direct protein self-translocation across the plasma membranes of mammalian cells.
Sparn C, Meyer A, Saleppico R, Nickel W.
Sparn C, et al. Among authors: saleppico r.
Trends Biochem Sci. 2022 Aug;47(8):699-709. doi: 10.1016/j.tibs.2022.04.001. Epub 2022 Apr 27.
Trends Biochem Sci. 2022.
PMID: 35490075
Review.
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Glypican-1 drives unconventional secretion of fibroblast growth factor 2.
Sparn C, Dimou E, Meyer A, Saleppico R, Wegehingel S, Gerstner M, Klaus S, Ewers H, Nickel W.
Sparn C, et al. Among authors: saleppico r.
Elife. 2022 Mar 29;11:e75545. doi: 10.7554/eLife.75545.
Elife. 2022.
PMID: 35348113
Free PMC article.
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The Na,K-ATPase acts upstream of phosphoinositide PI(4,5)P2 facilitating unconventional secretion of Fibroblast Growth Factor 2.
Legrand C, Saleppico R, Sticht J, Lolicato F, Müller HM, Wegehingel S, Dimou E, Steringer JP, Ewers H, Vattulainen I, Freund C, Nickel W.
Legrand C, et al. Among authors: saleppico r.
Commun Biol. 2020 Mar 25;3(1):141. doi: 10.1038/s42003-020-0871-y.
Commun Biol. 2020.
PMID: 32214225
Free PMC article.
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