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Internalization and trafficking of CSPG-bound recombinant VAR2CSA lectins in cancer cells.
Wang CK, Nelepcu I, Hui D, Oo HZ, Truong S, Zhao S, Tahiry Z, Esfandnia S, Ghaidi F, Adomat H, Dagil R, Gustavsson T, Choudhary S, Salanti A, Sorensen PH, Al Nakouzi N, Daugaard M. Wang CK, et al. Among authors: salanti a. Sci Rep. 2022 Feb 23;12(1):3075. doi: 10.1038/s41598-022-07025-6. Sci Rep. 2022. PMID: 35197518 Free PMC article.
Targeting Human Cancer by a Glycosaminoglycan Binding Malaria Protein.
Salanti A, Clausen TM, Agerbæk MØ, Al Nakouzi N, Dahlbäck M, Oo HZ, Lee S, Gustavsson T, Rich JR, Hedberg BJ, Mao Y, Barington L, Pereira MA, LoBello J, Endo M, Fazli L, Soden J, Wang CK, Sander AF, Dagil R, Thrane S, Holst PJ, Meng L, Favero F, Weiss GJ, Nielsen MA, Freeth J, Nielsen TO, Zaia J, Tran NL, Trent J, Babcook JS, Theander TG, Sorensen PH, Daugaard M. Salanti A, et al. Cancer Cell. 2015 Oct 12;28(4):500-514. doi: 10.1016/j.ccell.2015.09.003. Cancer Cell. 2015. PMID: 26461094 Free PMC article.
Real-time and label free determination of ligand binding-kinetics to primary cancer tissue specimens; a novel tool for the assessment of biomarker targeting.
Clausen TM, Pereira MA, Oo HZ, Resende M, Gustavson T, Mao Y, Sugiura N, Liew J, Fazli L, Theander TG, Daugaard M, Salanti A. Clausen TM, et al. Among authors: salanti a. Sens Biosensing Res. 2016 Jul;9:23-30. doi: 10.1016/j.sbsr.2016.05.003. Sens Biosensing Res. 2016. PMID: 27441183 Free PMC article.
Placental Sequestration of Plasmodium falciparum Malaria Parasites Is Mediated by the Interaction Between VAR2CSA and Chondroitin Sulfate A on Syndecan-1.
Ayres Pereira M, Mandel Clausen T, Pehrson C, Mao Y, Resende M, Daugaard M, Riis Kristensen A, Spliid C, Mathiesen L, E Knudsen L, Damm P, G Theander T, R Hansson S, A Nielsen M, Salanti A. Ayres Pereira M, et al. Among authors: a nielsen m, salanti a. PLoS Pathog. 2016 Aug 24;12(8):e1005831. doi: 10.1371/journal.ppat.1005831. eCollection 2016 Aug. PLoS Pathog. 2016. PMID: 27556547 Free PMC article.
Oncofetal Chondroitin Sulfate Glycosaminoglycans Are Key Players in Integrin Signaling and Tumor Cell Motility.
Clausen TM, Pereira MA, Al Nakouzi N, Oo HZ, Agerbæk MØ, Lee S, Ørum-Madsen MS, Kristensen AR, El-Naggar A, Grandgenett PM, Grem JL, Hollingsworth MA, Holst PJ, Theander T, Sorensen PH, Daugaard M, Salanti A. Clausen TM, et al. Among authors: salanti a. Mol Cancer Res. 2016 Dec;14(12):1288-1299. doi: 10.1158/1541-7786.MCR-16-0103. Epub 2016 Sep 21. Mol Cancer Res. 2016. PMID: 27655130 Free PMC article.
Burkitt lymphoma expresses oncofetal chondroitin sulfate without being a reservoir for placental malaria sequestration.
Agerbaek MØ, Pereira MA, Clausen TM, Pehrson C, Oo HZ, Spliid C, Rich JR, Fung V, Nkrumah F, Neequaye J, Biggar RJ, Reynolds SJ, Tosato G, Pullarkat ST, Ayers LW, Theander TG, Daugaard M, Bhatia K, Nielsen MA, Mbulaiteye SM, Salanti A. Agerbaek MØ, et al. Among authors: salanti a. Int J Cancer. 2017 Apr 1;140(7):1597-1608. doi: 10.1002/ijc.30575. Epub 2017 Feb 6. Int J Cancer. 2017. PMID: 27997697 Free PMC article.
An Oncofetal Glycosaminoglycan Modification Provides Therapeutic Access to Cisplatin-resistant Bladder Cancer.
Seiler R, Oo HZ, Tortora D, Clausen TM, Wang CK, Kumar G, Pereira MA, Ørum-Madsen MS, Agerbæk MØ, Gustavsson T, Nordmaj MA, Rich JR, Lallous N, Fazli L, Lee SS, Douglas J, Todenhöfer T, Esfandnia S, Battsogt D, Babcook JS, Al-Nakouzi N, Crabb SJ, Moskalev I, Kiss B, Davicioni E, Thalmann GN, Rennie PS, Black PC, Salanti A, Daugaard M. Seiler R, et al. Among authors: salanti a. Eur Urol. 2017 Jul;72(1):142-150. doi: 10.1016/j.eururo.2017.03.021. Epub 2017 Apr 10. Eur Urol. 2017. PMID: 28408175
The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner.
Agerbæk MØ, Bang-Christensen SR, Yang MH, Clausen TM, Pereira MA, Sharma S, Ditlev SB, Nielsen MA, Choudhary S, Gustavsson T, Sorensen PH, Meyer T, Propper D, Shamash J, Theander TG, Aicher A, Daugaard M, Heeschen C, Salanti A. Agerbæk MØ, et al. Among authors: salanti a. Nat Commun. 2018 Aug 16;9(1):3279. doi: 10.1038/s41467-018-05793-2. Nat Commun. 2018. PMID: 30115931 Free PMC article.
151 results