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Reading and erasing of the phosphonium analogue of trimethyllysine by epigenetic proteins.
Belle R, Kamps JJAG, Poater J, Kumar K, Pieters BJGE, Salah E, Claridge TDW, Paton RS, Matthias Bickelhaupt F, Kawamura A, Schofield CJ, Mecinović J. Belle R, et al. Among authors: salah e. Commun Chem. 2022 Mar 7;5(1):27. doi: 10.1038/s42004-022-00640-4. eCollection 2022 Dec. Commun Chem. 2022. PMID: 36071790 Free PMC article.
Human histone demethylase KDM6B can catalyse sequential oxidations.
Hopkinson RJ , Langley GW , Belle R , Walport LJ , Dunne K , Münzel M , Salah E , Kawamura A , Claridge TDW , Schofield CJ . Hopkinson RJ , et al. Among authors: salah e. Chem Commun (Camb). 2018 Jul 12;54(57):7975-7978. doi: 10.1039/c8cc04057e. Chem Commun (Camb). 2018. PMID: 29961803 Free PMC article.
Mass spectrometry reveals potential of β-lactams as SARS-CoV-2 Mpro inhibitors.
Malla TR, Tumber A, John T, Brewitz L, Strain-Damerell C, Owen CD, Lukacik P, Chan HTH, Maheswaran P, Salah E, Duarte F, Yang H, Rao Z, Walsh MA, Schofield CJ. Malla TR, et al. Among authors: salah e. Chem Commun (Camb). 2021 Feb 15;57(12):1430-1433. doi: 10.1039/d0cc06870e. Chem Commun (Camb). 2021. PMID: 33462575 Free PMC article.
Discovery of SARS-CoV-2 Mpro peptide inhibitors from modelling substrate and ligand binding.
Chan HTH, Moesser MA, Walters RK, Malla TR, Twidale RM, John T, Deeks HM, Johnston-Wood T, Mikhailov V, Sessions RB, Dawson W, Salah E, Lukacik P, Strain-Damerell C, Owen CD, Nakajima T, Świderek K, Lodola A, Moliner V, Glowacki DR, Spencer J, Walsh MA, Schofield CJ, Genovese L, Shoemark DK, Mulholland AJ, Duarte F, Morris GM. Chan HTH, et al. Among authors: salah e. Chem Sci. 2021 Sep 6;12(41):13686-13703. doi: 10.1039/d1sc03628a. eCollection 2021 Oct 27. Chem Sci. 2021. PMID: 34760153 Free PMC article.
Structure-Based Design of Selective Fat Mass and Obesity Associated Protein (FTO) Inhibitors.
Shishodia S, Demetriades M, Zhang D, Tam NY, Maheswaran P, Clunie-O'Connor C, Tumber A, Leung IKH, Ng YM, Leissing TM, El-Sagheer AH, Salah E, Brown T, Aik WS, McDonough MA, Schofield CJ. Shishodia S, et al. Among authors: salah e. J Med Chem. 2021 Nov 25;64(22):16609-16625. doi: 10.1021/acs.jmedchem.1c01204. Epub 2021 Nov 11. J Med Chem. 2021. PMID: 34762429 Free PMC article.
First-in-Class Inhibitors of the Ribosomal Oxygenase MINA53.
Nowak RP, Tumber A, Hendrix E, Ansari MSZ, Sabatino M, Antonini L, Andrijes R, Salah E, Mautone N, Pellegrini FR, Simelis K, Kawamura A, Johansson C, Passeri D, Pellicciari R, Ciogli A, Del Bufalo D, Ragno R, Coleman ML, Trisciuoglio D, Mai A, Oppermann U, Schofield CJ, Rotili D. Nowak RP, et al. Among authors: salah e. J Med Chem. 2021 Dec 9;64(23):17031-17050. doi: 10.1021/acs.jmedchem.1c00605. Epub 2021 Nov 29. J Med Chem. 2021. PMID: 34843649 Free PMC article.
142 results