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Phosphoinositide 3-Kinase Gamma Inhibition Protects From Anthracycline Cardiotoxicity and Reduces Tumor Growth.
Li M, Sala V, De Santis MC, Cimino J, Cappello P, Pianca N, Di Bona A, Margaria JP, Martini M, Lazzarini E, Pirozzi F, Rossi L, Franco I, Bornbaum J, Heger J, Rohrbach S, Perino A, Tocchetti CG, Lima BHF, Teixeira MM, Porporato PE, Schulz R, Angelini A, Sandri M, Ameri P, Sciarretta S, Lima-Júnior RCP, Mongillo M, Zaglia T, Morello F, Novelli F, Hirsch E, Ghigo A. Li M, et al. Among authors: sala v. Circulation. 2018 Aug 14;138(7):696-711. doi: 10.1161/CIRCULATIONAHA.117.030352. Circulation. 2018. PMID: 29348263 Free article.
Signaling Pathways Underlying Anthracycline Cardiotoxicity.
Sala V, Della Sala A, Hirsch E, Ghigo A. Sala V, et al. Antioxid Redox Signal. 2020 May 20;32(15):1098-1114. doi: 10.1089/ars.2020.8019. Epub 2020 Mar 5. Antioxid Redox Signal. 2020. PMID: 31989842 Review.
New avenues in cardio-oncology.
Sala V, Li M, Ghigo A. Sala V, et al. Aging (Albany NY). 2019 Feb 6;11(4):1075-1076. doi: 10.18632/aging.101817. Aging (Albany NY). 2019. PMID: 30728321 Free PMC article. No abstract available.
The novel butyrate derivative phenylalanine-butyramide protects from doxorubicin-induced cardiotoxicity.
Russo M, Guida F, Paparo L, Trinchese G, Aitoro R, Avagliano C, Fiordelisi A, Napolitano F, Mercurio V, Sala V, Li M, Sorriento D, Ciccarelli M, Ghigo A, Hirsch E, Bianco R, Iaccarino G, Abete P, Bonaduce D, Calignano A, Berni Canani R, Tocchetti CG. Russo M, et al. Among authors: sala v. Eur J Heart Fail. 2019 Apr;21(4):519-528. doi: 10.1002/ejhf.1439. Epub 2019 Mar 6. Eur J Heart Fail. 2019. PMID: 30843309 Free article.
Preventing and Treating Anthracycline Cardiotoxicity: New Insights.
Sawicki KT, Sala V, Prever L, Hirsch E, Ardehali H, Ghigo A. Sawicki KT, et al. Among authors: sala v. Annu Rev Pharmacol Toxicol. 2021 Jan 6;61:309-332. doi: 10.1146/annurev-pharmtox-030620-104842. Annu Rev Pharmacol Toxicol. 2021. PMID: 33022184 Review.
Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis.
Campa CC, Silva RL, Margaria JP, Pirali T, Mattos MS, Kraemer LR, Reis DC, Grosa G, Copperi F, Dalmarco EM, Lima-Júnior RCP, Aprile S, Sala V, Dal Bello F, Prado DS, Alves-Filho JC, Medana C, Cassali GD, Tron GC, Teixeira MM, Ciraolo E, Russo RC, Hirsch E. Campa CC, et al. Among authors: sala v. Nat Commun. 2018 Dec 12;9(1):5232. doi: 10.1038/s41467-018-07698-6. Nat Commun. 2018. PMID: 30542075 Free PMC article.
A PI3Kγ mimetic peptide triggers CFTR gating, bronchodilation, and reduced inflammation in obstructive airway diseases.
Ghigo A, Murabito A, Sala V, Pisano AR, Bertolini S, Gianotti A, Caci E, Montresor A, Premchandar A, Pirozzi F, Ren K, Della Sala A, Mergiotti M, Richter W, de Poel E, Matthey M, Caldrer S, Cardone RA, Civiletti F, Costamagna A, Quinney NL, Butnarasu C, Visentin S, Ruggiero MR, Baroni S, Crich SG, Ramel D, Laffargue M, Tocchetti CG, Levi R, Conti M, Lu XY, Melotti P, Sorio C, De Rose V, Facchinetti F, Fanelli V, Wenzel D, Fleischmann BK, Mall MA, Beekman J, Laudanna C, Gentzsch M, Lukacs GL, Pedemonte N, Hirsch E. Ghigo A, et al. Among authors: sala v. Sci Transl Med. 2022 Mar 30;14(638):eabl6328. doi: 10.1126/scitranslmed.abl6328. Epub 2022 Mar 30. Sci Transl Med. 2022. PMID: 35353541 Free PMC article.
Inhaled Biologicals for the Treatment of Cystic Fibrosis.
Sala V, Murabito A, Ghigo A. Sala V, et al. Recent Pat Inflamm Allergy Drug Discov. 2019;13(1):19-26. doi: 10.2174/1872213X12666181012101444. Recent Pat Inflamm Allergy Drug Discov. 2019. PMID: 30318010 Free PMC article. Review.
99 results