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Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer's disease.
De Schepper S, Ge JZ, Crowley G, Ferreira LSS, Garceau D, Toomey CE, Sokolova D, Rueda-Carrasco J, Shin SH, Kim JS, Childs T, Lashley T, Burden JJ, Sasner M, Sala Frigerio C, Jung S, Hong S. De Schepper S, et al. Among authors: sala frigerio c. Nat Neurosci. 2023 Mar;26(3):406-415. doi: 10.1038/s41593-023-01257-z. Epub 2023 Feb 6. Nat Neurosci. 2023. PMID: 36747024 Free PMC article.
Stem-cell-derived human microglia transplanted in mouse brain to study human disease.
Mancuso R, Van Den Daele J, Fattorelli N, Wolfs L, Balusu S, Burton O, Liston A, Sierksma A, Fourne Y, Poovathingal S, Arranz-Mendiguren A, Sala Frigerio C, Claes C, Serneels L, Theys T, Perry VH, Verfaillie C, Fiers M, De Strooper B. Mancuso R, et al. Among authors: sala frigerio c. Nat Neurosci. 2019 Dec;22(12):2111-2116. doi: 10.1038/s41593-019-0525-x. Epub 2019 Oct 28. Nat Neurosci. 2019. PMID: 31659342
A genetic link between risk for Alzheimer's disease and severe COVID-19 outcomes via the OAS1 gene.
Magusali N, Graham AC, Piers TM, Panichnantakul P, Yaman U, Shoai M, Reynolds RH, Botia JA, Brookes KJ, Guetta-Baranes T, Bellou E, Bayram S, Sokolova D, Ryten M, Sala Frigerio C, Escott-Price V, Morgan K, Pocock JM, Hardy J, Salih DA. Magusali N, et al. Among authors: sala frigerio c. Brain. 2021 Dec 31;144(12):3727-3741. doi: 10.1093/brain/awab337. Brain. 2021. PMID: 34619763 Free PMC article.
The Major Risk Factors for Alzheimer's Disease: Age, Sex, and Genes Modulate the Microglia Response to Aβ Plaques.
Sala Frigerio C, Wolfs L, Fattorelli N, Thrupp N, Voytyuk I, Schmidt I, Mancuso R, Chen WT, Woodbury ME, Srivastava G, Möller T, Hudry E, Das S, Saido T, Karran E, Hyman B, Perry VH, Fiers M, De Strooper B. Sala Frigerio C, et al. Cell Rep. 2019 Apr 23;27(4):1293-1306.e6. doi: 10.1016/j.celrep.2019.03.099. Cell Rep. 2019. PMID: 31018141 Free PMC article.
Spatial Transcriptomics and In Situ Sequencing to Study Alzheimer's Disease.
Chen WT, Lu A, Craessaerts K, Pavie B, Sala Frigerio C, Corthout N, Qian X, Laláková J, Kühnemund M, Voytyuk I, Wolfs L, Mancuso R, Salta E, Balusu S, Snellinx A, Munck S, Jurek A, Fernandez Navarro J, Saido TC, Huitinga I, Lundeberg J, Fiers M, De Strooper B. Chen WT, et al. Among authors: sala frigerio c. Cell. 2020 Aug 20;182(4):976-991.e19. doi: 10.1016/j.cell.2020.06.038. Epub 2020 Jul 22. Cell. 2020. PMID: 32702314 Free article.
Reduced expression of hsa-miR-27a-3p in CSF of patients with Alzheimer disease.
Sala Frigerio C, Lau P, Salta E, Tournoy J, Bossers K, Vandenberghe R, Wallin A, Bjerke M, Zetterberg H, Blennow K, De Strooper B. Sala Frigerio C, et al. Neurology. 2013 Dec 10;81(24):2103-6. doi: 10.1212/01.wnl.0000437306.37850.22. Epub 2013 Nov 8. Neurology. 2013. PMID: 24212398
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