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Viral subversion of nucleocytoplasmic trafficking.
Yarbrough ML, Mata MA, Sakthivel R, Fontoura BM. Yarbrough ML, et al. Among authors: sakthivel r. Traffic. 2014 Feb;15(2):127-40. doi: 10.1111/tra.12137. Epub 2013 Dec 2. Traffic. 2014. PMID: 24289861 Free PMC article. Review.
Primate-specific miR-576-3p sets host defense signalling threshold.
Yarbrough ML, Zhang K, Sakthivel R, Forst CV, Posner BA, Barber GN, White MA, Fontoura BM. Yarbrough ML, et al. Among authors: sakthivel r. Nat Commun. 2014 Sep 18;5:4963. doi: 10.1038/ncomms5963. Nat Commun. 2014. PMID: 25232931 Free PMC article.
Influenza virus differentially activates mTORC1 and mTORC2 signaling to maximize late stage replication.
Kuss-Duerkop SK, Wang J, Mena I, White K, Metreveli G, Sakthivel R, Mata MA, Muñoz-Moreno R, Chen X, Krammer F, Diamond MS, Chen ZJ, García-Sastre A, Fontoura BMA. Kuss-Duerkop SK, et al. Among authors: sakthivel r. PLoS Pathog. 2017 Sep 27;13(9):e1006635. doi: 10.1371/journal.ppat.1006635. eCollection 2017 Sep. PLoS Pathog. 2017. PMID: 28953980 Free PMC article.
Influenza Virus NS1 Protein-RNA Interactome Reveals Intron Targeting.
Zhang L, Wang J, Muñoz-Moreno R, Kim M, Sakthivel R, Mo W, Shao D, Anantharaman A, García-Sastre A, Conrad NK, Fontoura BMA. Zhang L, et al. Among authors: sakthivel r. J Virol. 2018 Nov 27;92(24):e01634-18. doi: 10.1128/JVI.01634-18. Print 2018 Dec 15. J Virol. 2018. PMID: 30258002 Free PMC article.
Structural-functional interactions of NS1-BP protein with the splicing and mRNA export machineries for viral and host gene expression.
Zhang K, Shang G, Padavannil A, Wang J, Sakthivel R, Chen X, Kim M, Thompson MG, García-Sastre A, Lynch KW, Chen ZJ, Chook YM, Fontoura BMA. Zhang K, et al. Among authors: sakthivel r. Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):E12218-E12227. doi: 10.1073/pnas.1818012115. Epub 2018 Dec 11. Proc Natl Acad Sci U S A. 2018. PMID: 30538201 Free PMC article.
Chemical intervention of influenza virus mRNA nuclear export.
Esparza M, Mor A, Niederstrasser H, White K, White A, Zhang K, Gao S, Wang J, Liang J, Sho S, Sakthivel R, Sathe AA, Xing C, Muñoz-Moreno R, Shay JW, García-Sastre A, Ready J, Posner B, Fontoura BMA. Esparza M, et al. Among authors: sakthivel r. PLoS Pathog. 2020 Apr 2;16(4):e1008407. doi: 10.1371/journal.ppat.1008407. eCollection 2020 Apr. PLoS Pathog. 2020. PMID: 32240278 Free PMC article.
The Plasmodium eukaryotic initiation factor-2alpha kinase IK2 controls the latency of sporozoites in the mosquito salivary glands.
Zhang M, Fennell C, Ranford-Cartwright L, Sakthivel R, Gueirard P, Meister S, Caspi A, Doerig C, Nussenzweig RS, Tuteja R, Sullivan WJ Jr, Roos DS, Fontoura BM, Ménard R, Winzeler EA, Nussenzweig V. Zhang M, et al. Among authors: sakthivel r. J Exp Med. 2010 Jul 5;207(7):1465-74. doi: 10.1084/jem.20091975. Epub 2010 Jun 28. J Exp Med. 2010. PMID: 20584882 Free PMC article.
PK4, a eukaryotic initiation factor 2α(eIF2α) kinase, is essential for the development of the erythrocytic cycle of Plasmodium.
Zhang M, Mishra S, Sakthivel R, Rojas M, Ranjan R, Sullivan WJ Jr, Fontoura BM, Ménard R, Dever TE, Nussenzweig V. Zhang M, et al. Among authors: sakthivel r. Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3956-61. doi: 10.1073/pnas.1121567109. Epub 2012 Feb 21. Proc Natl Acad Sci U S A. 2012. PMID: 22355110 Free PMC article.
139 results