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Atherosclerotic Plaque Epigenetic Age Acceleration Predicts a Poor Prognosis and Is Associated With Endothelial-to-Mesenchymal Transition in Humans.
Benavente ED, Hartman RJG, Sakkers TR, Wesseling M, Sloots Y, Slenders L, Boltjes A, Mol BM, de Borst GJ, de Kleijn DPV, Prange KHM, de Winther MPJ, Kuiper J, Civelek M, van der Laan SW, Horvath S, Onland-Moret C, Mokry M, Pasterkamp G, den Ruijter HM. Benavente ED, et al. Among authors: sakkers tr. Arterioscler Thromb Vasc Biol. 2024 Apr 18. doi: 10.1161/ATVBAHA.123.320692. Online ahead of print. Arterioscler Thromb Vasc Biol. 2024. PMID: 38634280 Free article.
The accumulation of erythrocytes quantified and visualized by Glycophorin C in carotid atherosclerotic plaque reflects intraplaque hemorrhage and pre-procedural neurological symptoms.
Mekke JM, Sakkers TR, Verwer MC, van den Dungen NAM, Song Y, Miller CL, Finn AV, Pasterkamp G, Mokry M, den Ruijter HM, Vink A, de Kleijn DPV, de Borst GJ, Haitjema S, van der Laan SW. Mekke JM, et al. Among authors: sakkers tr. Sci Rep. 2023 Oct 10;13(1):17104. doi: 10.1038/s41598-023-43369-3. Sci Rep. 2023. PMID: 37816779 Free PMC article.