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Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndrome.
Tanaka T, Yamamoto J, Iwasaki S, Asaba H, Hamura H, Ikeda Y, Watanabe M, Magoori K, Ioka RX, Tachibana K, Watanabe Y, Uchiyama Y, Sumi K, Iguchi H, Ito S, Doi T, Hamakubo T, Naito M, Auwerx J, Yanagisawa M, Kodama T, Sakai J. Tanaka T, et al. Among authors: sakai j. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15924-9. doi: 10.1073/pnas.0306981100. Epub 2003 Dec 15. Proc Natl Acad Sci U S A. 2003. PMID: 14676330 Free PMC article.
SOX6 attenuates glucose-stimulated insulin secretion by repressing PDX1 transcriptional activity and is down-regulated in hyperinsulinemic obese mice.
Iguchi H, Ikeda Y, Okamura M, Tanaka T, Urashima Y, Ohguchi H, Takayasu S, Kojima N, Iwasaki S, Ohashi R, Jiang S, Hasegawa G, Ioka RX, Magoori K, Sumi K, Maejima T, Uchida A, Naito M, Osborne TF, Yanagisawa M, Yamamoto TT, Kodama T, Sakai J. Iguchi H, et al. Among authors: sakai j. J Biol Chem. 2005 Nov 11;280(45):37669-80. doi: 10.1074/jbc.M505392200. Epub 2005 Sep 7. J Biol Chem. 2005. PMID: 16148004 Free article.
Gene expression profiling of potential peroxisome proliferator-activated receptor (PPAR) target genes in human hepatoblastoma cell lines inducibly expressing different PPAR isoforms.
Tachibana K, Kobayashi Y, Tanaka T, Tagami M, Sugiyama A, Katayama T, Ueda C, Yamasaki D, Ishimoto K, Sumitomo M, Uchiyama Y, Kohro T, Sakai J, Hamakubo T, Kodama T, Doi T. Tachibana K, et al. Among authors: sakai j. Nucl Recept. 2005 Oct 3;3:3. doi: 10.1186/1478-1336-3-3. Nucl Recept. 2005. PMID: 16197558 Free PMC article.
Dysregulated expression of P1 and P2 promoter-driven hepatocyte nuclear factor-4alpha in the pathogenesis of human cancer.
Tanaka T, Jiang S, Hotta H, Takano K, Iwanari H, Sumi K, Daigo K, Ohashi R, Sugai M, Ikegame C, Umezu H, Hirayama Y, Midorikawa Y, Hippo Y, Watanabe A, Uchiyama Y, Hasegawa G, Reid P, Aburatani H, Hamakubo T, Sakai J, Naito M, Kodama T. Tanaka T, et al. Among authors: sakai j. J Pathol. 2006 Apr;208(5):662-72. doi: 10.1002/path.1928. J Pathol. 2006. PMID: 16400631
Analysis of PPAR alpha function in human kidney cell line using siRNA.
Tachibana K, Anzai N, Ueda C, Katayama T, Kirino T, Takahashi R, Yamasaki D, Ishimoto K, Tanaka T, Hamakubo T, Ueda Y, Arai H, Sakai J, Kodama T, Doi T. Tachibana K, et al. Among authors: sakai j. Nucleic Acids Symp Ser (Oxf). 2006;(50):257-8. doi: 10.1093/nass/nrl128. Nucleic Acids Symp Ser (Oxf). 2006. PMID: 17150915
600 results