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Construction of a T cell receptor signaling range for spontaneous development of autoimmune disease.
Tanaka A, Maeda S, Nomura T, Llamas-Covarrubias MA, Tanaka S, Jin L, Lim EL, Morikawa H, Kitagawa Y, Akizuki S, Ito Y, Fujimori C, Hirota K, Murase T, Hashimoto M, Higo J, Zamoyska R, Ueda R, Standley DM, Sakaguchi N, Sakaguchi S. Tanaka A, et al. Among authors: sakaguchi n, sakaguchi s. J Exp Med. 2023 Feb 6;220(2):e20220386. doi: 10.1084/jem.20220386. Epub 2022 Dec 1. J Exp Med. 2023. PMID: 36454183 Free PMC article.
A role for fungal {beta}-glucans and their receptor Dectin-1 in the induction of autoimmune arthritis in genetically susceptible mice.
Yoshitomi H, Sakaguchi N, Kobayashi K, Brown GD, Tagami T, Sakihama T, Hirota K, Tanaka S, Nomura T, Miki I, Gordon S, Akira S, Nakamura T, Sakaguchi S. Yoshitomi H, et al. Among authors: sakaguchi n, sakaguchi s. J Exp Med. 2005 Mar 21;201(6):949-60. doi: 10.1084/jem.20041758. J Exp Med. 2005. PMID: 15781585 Free PMC article.
Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model.
Hirota K, Yoshitomi H, Hashimoto M, Maeda S, Teradaira S, Sugimoto N, Yamaguchi T, Nomura T, Ito H, Nakamura T, Sakaguchi N, Sakaguchi S. Hirota K, et al. Among authors: sakaguchi n, sakaguchi s. J Exp Med. 2007 Nov 26;204(12):2803-12. doi: 10.1084/jem.20071397. Epub 2007 Nov 19. J Exp Med. 2007. PMID: 18025126 Free PMC article.
Complement drives Th17 cell differentiation and triggers autoimmune arthritis.
Hashimoto M, Hirota K, Yoshitomi H, Maeda S, Teradaira S, Akizuki S, Prieto-Martin P, Nomura T, Sakaguchi N, Köhl J, Heyman B, Takahashi M, Fujita T, Mimori T, Sakaguchi S. Hashimoto M, et al. Among authors: sakaguchi n, sakaguchi s. J Exp Med. 2010 Jun 7;207(6):1135-43. doi: 10.1084/jem.20092301. Epub 2010 May 10. J Exp Med. 2010. PMID: 20457757 Free PMC article.
Graded attenuation of TCR signaling elicits distinct autoimmune diseases by altering thymic T cell selection and regulatory T cell function.
Tanaka S, Maeda S, Hashimoto M, Fujimori C, Ito Y, Teradaira S, Hirota K, Yoshitomi H, Katakai T, Shimizu A, Nomura T, Sakaguchi N, Sakaguchi S. Tanaka S, et al. Among authors: sakaguchi n, sakaguchi s. J Immunol. 2010 Aug 15;185(4):2295-305. doi: 10.4049/jimmunol.1000848. Epub 2010 Jul 19. J Immunol. 2010. PMID: 20644168
Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease.
Ito Y, Hashimoto M, Hirota K, Ohkura N, Morikawa H, Nishikawa H, Tanaka A, Furu M, Ito H, Fujii T, Nomura T, Yamazaki S, Morita A, Vignali DA, Kappler JW, Matsuda S, Mimori T, Sakaguchi N, Sakaguchi S. Ito Y, et al. Among authors: sakaguchi n, sakaguchi s. Science. 2014 Oct 17;346(6207):363-8. doi: 10.1126/science.1259077. Science. 2014. PMID: 25324392 Free PMC article.
382 results