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Crucial role of RAGE in inappropriate increase of smooth muscle cells from patients with pulmonary arterial hypertension.
Nakamura K, Sakaguchi M, Matsubara H, Akagi S, Sarashina T, Ejiri K, Akazawa K, Kondo M, Nakagawa K, Yoshida M, Miyoshi T, Ogo T, Oto T, Toyooka S, Higashimoto Y, Fukami K, Ito H. Nakamura K, et al. Among authors: sakaguchi m. PLoS One. 2018 Sep 4;13(9):e0203046. doi: 10.1371/journal.pone.0203046. eCollection 2018. PLoS One. 2018. PMID: 30180189 Free PMC article.
Epigenetic silencing of microRNA-34b/c plays an important role in the pathogenesis of malignant pleural mesothelioma.
Kubo T, Toyooka S, Tsukuda K, Sakaguchi M, Fukazawa T, Soh J, Asano H, Ueno T, Muraoka T, Yamamoto H, Nasu Y, Kishimoto T, Pass HI, Matsui H, Huh NH, Miyoshi S. Kubo T, et al. Among authors: sakaguchi m. Clin Cancer Res. 2011 Aug 1;17(15):4965-74. doi: 10.1158/1078-0432.CCR-10-3040. Epub 2011 Jun 14. Clin Cancer Res. 2011. PMID: 21673066
Novel germline mutation in the transmembrane domain of HER2 in familial lung adenocarcinomas.
Yamamoto H, Higasa K, Sakaguchi M, Shien K, Soh J, Ichimura K, Furukawa M, Hashida S, Tsukuda K, Takigawa N, Matsuo K, Kiura K, Miyoshi S, Matsuda F, Toyooka S. Yamamoto H, et al. Among authors: sakaguchi m. J Natl Cancer Inst. 2014 Jan;106(1):djt338. doi: 10.1093/jnci/djt338. Epub 2013 Dec 7. J Natl Cancer Inst. 2014. PMID: 24317180 Free PMC article.
Preclinical evaluation of microRNA-34b/c delivery for malignant pleural mesothelioma.
Ueno T, Toyooka S, Fukazawa T, Kubo T, Soh J, Asano H, Muraoka T, Tanaka N, Maki Y, Shien K, Furukawa M, Sakaguchi M, Yamamoto H, Tsukuda K, Miyoshi S. Ueno T, et al. Among authors: sakaguchi m. Acta Med Okayama. 2014;68(1):23-6. doi: 10.18926/AMO/52140. Acta Med Okayama. 2014. PMID: 24553485 Free article.
TAE226, a Bis-Anilino Pyrimidine Compound, Inhibits the EGFR-Mutant Kinase Including T790M Mutant to Show Anti-Tumor Effect on EGFR-Mutant Non-Small Cell Lung Cancer Cells.
Otani H, Yamamoto H, Takaoka M, Sakaguchi M, Soh J, Jida M, Ueno T, Kubo T, Asano H, Tsukuda K, Kiura K, Hatakeyama S, Kawahara E, Naomoto Y, Miyoshi S, Toyooka S. Otani H, et al. Among authors: sakaguchi m. PLoS One. 2015 Jun 19;10(6):e0129838. doi: 10.1371/journal.pone.0129838. eCollection 2015. PLoS One. 2015. PMID: 26090892 Free PMC article.
Antitumor effect of afatinib, as a human epidermal growth factor receptor 2-targeted therapy, in lung cancers harboring HER2 oncogene alterations.
Suzawa K, Toyooka S, Sakaguchi M, Morita M, Yamamoto H, Tomida S, Ohtsuka T, Watanabe M, Hashida S, Maki Y, Soh J, Asano H, Tsukuda K, Miyoshi S. Suzawa K, et al. Among authors: sakaguchi m. Cancer Sci. 2016 Jan;107(1):45-52. doi: 10.1111/cas.12845. Epub 2015 Dec 3. Cancer Sci. 2016. PMID: 26545934 Free PMC article.
Interaction of cytokeratin 19 head domain and HER2 in the cytoplasm leads to activation of HER2-Erk pathway.
Ohtsuka T, Sakaguchi M, Yamamoto H, Tomida S, Takata K, Shien K, Hashida S, Miyata-Takata T, Watanabe M, Suzawa K, Soh J, Youyi C, Sato H, Namba K, Torigoe H, Tsukuda K, Yoshino T, Miyoshi S, Toyooka S. Ohtsuka T, et al. Among authors: sakaguchi m. Sci Rep. 2016 Dec 23;6:39557. doi: 10.1038/srep39557. Sci Rep. 2016. PMID: 28008968 Free PMC article.
β-1,3-Galactosyl-O-Glycosyl-Glycoprotein β-1,6-N-Acetylglucosaminyltransferase 3 Increases MCAM Stability, Which Enhances S100A8/A9-Mediated Cancer Motility.
Sumardika IW, Youyi C, Kondo E, Inoue Y, Ruma IMW, Murata H, Kinoshita R, Yamamoto KI, Tomida S, Shien K, Sato H, Yamauchi A, Futami J, Putranto EW, Hibino T, Toyooka S, Nishibori M, Sakaguchi M. Sumardika IW, et al. Among authors: sakaguchi m. Oncol Res. 2018 Apr 10;26(3):431-444. doi: 10.3727/096504017X15031557924123. Epub 2017 Sep 18. Oncol Res. 2018. PMID: 28923134 Free PMC article.
1,677 results