Sajith AM - Search Results

1

Application of NMI-TfCl-mediated amide bond formation in the synthesis of biologically relevant oxadiazole derivatives employing less basic (hetero)aryl amines.

Rajendra MA, Naseem M, Joy MN, Sunil K, Sajith AM, Howari F, Nazzal Y, Xavier C, Alshammari MB, Haridas KR. Rajendra MA, et al. Among authors: sajith am. Mol Divers. 2022 Jun;26(3):1761-1767. doi: 10.1007/s11030-021-10275-7. Epub 2021 Jul 22. Mol Divers. 2022. PMID: 34296385

2

A highly efficient precatalytic system (XPhos-PdG2) for the Suzuki-Miyaura cross-coupling of 7-chloro-1H-pyrrolo[2,3-c]pyridine employing low catalyst loading.

Savitha B, Reddy EK, Parthasarathi D, Pakkath R, Karuvalam RP, Ananda Kumar CS, Haridas KR, Syed Ali Padusha M, Sajith AM. Savitha B, et al. Among authors: sajith am. Mol Divers. 2019 Aug;23(3):697-707. doi: 10.1007/s11030-018-9904-6. Epub 2019 Jan 9. Mol Divers. 2019. PMID: 30627855

3

Pyrimidine-2,4-dione targets STAT3 signaling pathway to induce cytotoxicity in hepatocellular carcinoma cells.

Sajith AM, Narasimhamurthy KH, Shanmugam MK, Rangappa S, Chandra Nayak S, Chinnathambi A, Awad Alahmadi T, Ali Alharbi S, Haridas KR, Reddy EK, Savitha B, Mohan CD, Rangappa KS. Sajith AM, et al. Bioorg Med Chem Lett. 2021 Oct 15;50:128332. doi: 10.1016/j.bmcl.2021.128332. Epub 2021 Aug 19. Bioorg Med Chem Lett. 2021. PMID: 34418571

4

Design, synthesis and molecular docking studies of some 1-(5-(2-fluoro-5-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-3-yl)piperazine derivatives as potential anti-inflammatory agents.

Kulkarni B, Manjunatha K, Joy MN, Sajith AM, Prashantha CN, Pakkath R, Alshammari MB. Kulkarni B, et al. Among authors: sajith am. Mol Divers. 2022 Oct;26(5):2893-2905. doi: 10.1007/s11030-021-10340-1. Epub 2021 Nov 24. Mol Divers. 2022. PMID: 34817768

5

Towards novel tacrine analogues: Pd(dppf)Cl₂·CH₂Cl₂ catalyzed improved synthesis, in silico docking and hepatotoxicity studies.

Babu A, Joy MN, Sunil K, Sajith AM, Santra S, Zyryanov GV, Konovalova OA, Butorin II, Muniraju K. Babu A, et al. Among authors: sajith am. RSC Adv. 2022 Aug 11;12(35):22476-22491. doi: 10.1039/d2ra03225b. eCollection 2022 Aug 10. RSC Adv. 2022. PMID: 36105950 Free PMC article.

6

Exploration of NMI-MsCl mediated amide bond formation for the synthesis of novel 3,5-substituted-1,2,4-oxadiazole derivatives: synthesis, evaluation of anti-inflammatory activity and molecular docking studies.

Kulkarni B, Manjunatha K, Joy MN, Sajith AM, Santra S, Zyryanov GV, Prashantha CN, Alshammari MB, Sunil K. Kulkarni B, et al. Among authors: sajith am. Mol Divers. 2023 Aug;27(4):1867-1878. doi: 10.1007/s11030-022-10536-z. Epub 2022 Oct 11. Mol Divers. 2023. PMID: 36219380

7

Sub-pocket-focused designing of tacrine derivatives as potential acetylcholinesterase inhibitors.

Babu A, John M, Liji MJ, Maria E, Bhaskar SJ, Binukmar BK, Sajith AM, Reddy EK, Dileep KV, Sunil K. Babu A, et al. Among authors: sajith am. Comput Biol Med. 2023 Mar;155:106666. doi: 10.1016/j.compbiomed.2023.106666. Epub 2023 Feb 11. Comput Biol Med. 2023. PMID: 36841058

8

Co₂(CO)₈ as a Solid CO (g) Source for the Amino Carbonylation of (Hetero)aryl Halides with Highly Deactivated (Hetero)arylamines.

Cheruku S, Sajith AM, Narayana Y, Shetty P, Nagarakere SC, Sagar KS, Manikyanally KN, Rangappa KS, Mantelingu K. Cheruku S, et al. Among authors: sajith am. J Org Chem. 2021 Apr 16;86(8):5530-5537. doi: 10.1021/acs.joc.0c02999. Epub 2021 Apr 7. J Org Chem. 2021. PMID: 33826333

9

Design, synthesis and structure--activity relationship (SAR) studies of imidazo[4,5-b]pyridine derived purine isosteres and their potential as cytotoxic agents.

Sajith AM, Abdul Khader KK, Joshi N, Reddy MN, Syed Ali Padusha M, Nagaswarupa HP, Nibin Joy M, Bodke YD, Karuvalam RP, Banerjee R, Muralidharan A, Rajendra P. Sajith AM, et al. Eur J Med Chem. 2015 Jan 7;89:21-31. doi: 10.1016/j.ejmech.2014.10.037. Epub 2014 Oct 14. Eur J Med Chem. 2015. PMID: 25462222

10

Novel tacrine derivatives exhibiting improved acetylcholinesterase inhibition: Design, synthesis and biological evaluation.

Reddy EK, Remya C, Mantosh K, Sajith AM, Omkumar RV, Sadasivan C, Anwar S. Reddy EK, et al. Among authors: sajith am. Eur J Med Chem. 2017 Oct 20;139:367-377. doi: 10.1016/j.ejmech.2017.08.013. Epub 2017 Aug 5. Eur J Med Chem. 2017. PMID: 28810188

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