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Indenoquinoxaline-phenylacrylohydrazide hybrids as promising drug candidates for the treatment of type 2 diabetes: In vitro and in silico evaluation of enzyme inhibition and antioxidant activity.
Hameed S, Saleem F, Özil M, Baltaş N, Salar U, Ashraf S, Ul-Haq Z, Taha M, Khan KM. Hameed S, et al. Among authors: ashraf s. Int J Biol Macromol. 2024 Apr;263(Pt 2):129517. doi: 10.1016/j.ijbiomac.2024.129517. Epub 2024 Jan 22. Int J Biol Macromol. 2024. PMID: 38266833
New spiro-indeno[1,2-b]quinoxalines clubbed with benzimidazole scaffold as CDK2 inhibitors for halting non-small cell lung cancer; stereoselective synthesis, molecular dynamics and structural insights.
Barakat A, Alshahrani S, Al-Majid AM, Alamary AS, Haukka M, Abu-Serie MM, Domingo LR, Ashraf S, Ul-Haq Z, Nafie MS, Teleb M. Barakat A, et al. Among authors: ashraf s. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2281260. doi: 10.1080/14756366.2023.2281260. Epub 2023 Nov 23. J Enzyme Inhib Med Chem. 2023. PMID: 37994663 Free PMC article.
Synthesis, crystal structure, DFT, Hirshfeld surface analysis, energy frameworks and in-Silico drug-targeting PFKFB3 kinase of novel triazolequinoxalin derivative (TZQ) as a therapeutic Strategy against cancer.
Abad N, Al-Ostoot FH, Ashraf S, Chkirate K, Aljohani MS, Alharbi HY, Buhlak S, El Hafi M, Van Meervelt L, Al-Maswari BM, Essassi EM, Ramli Y. Abad N, et al. Among authors: ashraf s. Heliyon. 2023 Oct 20;9(11):e21312. doi: 10.1016/j.heliyon.2023.e21312. eCollection 2023 Nov. Heliyon. 2023. PMID: 37920528 Free PMC article.
39 results