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Aerosol delivery of SARS-CoV-2 human monoclonal antibodies in macaques limits viral replication and lung pathology.
Streblow DN, Hirsch AJ, Stanton JJ, Lewis AD, Colgin L, Hessell AJ, Kreklywich CN, Smith JL, Sutton WF, Chauvin D, Woo J, Bimber BN, LeBlanc CN, Acharya SN, O'Roak BJ, Sardar H, Sajadi MM, Tehrani ZR, Walter MR, Martinez-Sobrido L, Kobie JJ, Reader RJ, Olstad KJ, Hobbs TR, Saphire EO, Schendel SL, Carnahan RH, Knoch J, Branco LM, Crowe JE Jr, Van Rompay KKA, Lovalenti P, Vu Truong, Forthal DN, Haigwood NL. Streblow DN, et al. Among authors: sajadi mm. Nat Commun. 2023 Nov 3;14(1):7062. doi: 10.1038/s41467-023-42440-x. Nat Commun. 2023. PMID: 37923717 Free PMC article.
Structural characterization of protective non-neutralizing antibodies targeting Crimean-Congo hemorrhagic fever virus.
Durie IA, Tehrani ZR, Karaaslan E, Sorvillo TE, McGuire J, Golden JW, Welch SR, Kainulainen MH, Harmon JR, Mousa JJ, Gonzalez D, Enos S, Koksal I, Yilmaz G, Karakoc HN, Hamidi S, Albay C, Spengler JR, Spiropoulou CF, Garrison AR, Sajadi MM, Bergeron É, Pegan SD. Durie IA, et al. Among authors: sajadi mm. Nat Commun. 2022 Nov 26;13(1):7298. doi: 10.1038/s41467-022-34923-0. Nat Commun. 2022. PMID: 36435827 Free PMC article.
SARS-CoV-2 infection and persistence in the human body and brain at autopsy.
Stein SR, Ramelli SC, Grazioli A, Chung JY, Singh M, Yinda CK, Winkler CW, Sun J, Dickey JM, Ylaya K, Ko SH, Platt AP, Burbelo PD, Quezado M, Pittaluga S, Purcell M, Munster VJ, Belinky F, Ramos-Benitez MJ, Boritz EA, Lach IA, Herr DL, Rabin J, Saharia KK, Madathil RJ, Tabatabai A, Soherwardi S, McCurdy MT; NIH COVID-19 Autopsy Consortium; Peterson KE, Cohen JI, de Wit E, Vannella KM, Hewitt SM, Kleiner DE, Chertow DS. Stein SR, et al. Nature. 2022 Dec;612(7941):758-763. doi: 10.1038/s41586-022-05542-y. Epub 2022 Dec 14. Nature. 2022. PMID: 36517603 Free PMC article.
Replacement of Antiretroviral Therapy with HIV Broadly Neutralizing Antibodies to Maximize the Effectiveness of Chemotherapy in HIV Patients with Lung Cancer.
Atkinson B, Abassi A, Sajadi MM, Tehrani ZR, Le NM, Chen HH, Sausville E, DeVico AL, Lewis GK, Fan X, Heredia A. Atkinson B, et al. Among authors: sajadi mm. AIDS Res Hum Retroviruses. 2023 Sep;39(9):475-481. doi: 10.1089/AID.2022.0181. Epub 2023 May 5. AIDS Res Hum Retroviruses. 2023. PMID: 37053110
The molecular basis of the neutralization breadth of the RBD-specific antibody CoV11.
Tolbert WD, Chen Y, Sun L, Benlarbi M, Ding S, Manickam R, Pangaro E, Nguyen DN, Gottumukkala S, Côté M, Gonzalez FJ, Finzi A, Tehrani ZR, Sajadi MM, Pazgier M. Tolbert WD, et al. Among authors: sajadi mm. Front Immunol. 2023 Jun 2;14:1178355. doi: 10.3389/fimmu.2023.1178355. eCollection 2023. Front Immunol. 2023. PMID: 37334379 Free PMC article.
Histopathology and SARS-CoV-2 Cellular Localization in Eye Tissues of COVID-19 Autopsies.
Sen HN, Vannella KM, Wang Y, Chung JY, Kodati S, Ramelli SC, Lee JW, Perez P, Stein SR, Grazioli A, Dickey JM, Ylaya K, Singh M, Yinda KC, Platt A, Ramos-Benitez MJ, Zerbe C, Munster VJ, de Wit E, Warner BM, Herr DL, Rabin J, Saharia KK; NIH COVID-19 Autopsy Consortium; Kleiner DE, Hewitt SM, Chan CC, Chertow DS. Sen HN, et al. Am J Pathol. 2023 Nov;193(11):1809-1816. doi: 10.1016/j.ajpath.2023.02.016. Epub 2023 Mar 22. Am J Pathol. 2023. PMID: 36963628 Free PMC article.
IFNα induces CCR5 in CD4+ T cells of HIV patients causing pathogenic elevation.
Le Buanec H, Schiavon V, Merandet M, How-Kit A, Song H, Bergerat D, Fombellida-Lopez C, Bensussan A, Bouaziz JD, Burny A, Darcis G, Sajadi MM, Kottilil S, Zagury D, Gallo RC. Le Buanec H, et al. Among authors: sajadi mm. Commun Med (Lond). 2024 Mar 19;4(1):52. doi: 10.1038/s43856-024-00453-7. Commun Med (Lond). 2024. PMID: 38504093 Free PMC article.
Early elevated IFNα is a key mediator of HIV pathogenesis.
Buanec HL, Schiavon V, Merandet M, How-Kit A, Bergerat D, Fombellida-Lopez C, Bensussan A, Bouaziz JD, Burny A, Darcis G, Song H, Sajadi MM, Kottilil S, Gallo RC, Zagury D. Buanec HL, et al. Among authors: sajadi mm. Commun Med (Lond). 2024 Mar 19;4(1):53. doi: 10.1038/s43856-024-00454-6. Commun Med (Lond). 2024. PMID: 38504106 Free PMC article.
83 results