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Early elevated IFNα is a key mediator of HIV pathogenesis.
Buanec HL, Schiavon V, Merandet M, How-Kit A, Bergerat D, Fombellida-Lopez C, Bensussan A, Bouaziz JD, Burny A, Darcis G, Song H, Sajadi MM, Kottilil S, Gallo RC, Zagury D. Buanec HL, et al. Among authors: sajadi mm. Commun Med (Lond). 2024 Mar 19;4(1):53. doi: 10.1038/s43856-024-00454-6. Commun Med (Lond). 2024. PMID: 38504106 Free PMC article.
IFNα induces CCR5 in CD4+ T cells of HIV patients causing pathogenic elevation.
Le Buanec H, Schiavon V, Merandet M, How-Kit A, Song H, Bergerat D, Fombellida-Lopez C, Bensussan A, Bouaziz JD, Burny A, Darcis G, Sajadi MM, Kottilil S, Zagury D, Gallo RC. Le Buanec H, et al. Among authors: sajadi mm. Commun Med (Lond). 2024 Mar 19;4(1):52. doi: 10.1038/s43856-024-00453-7. Commun Med (Lond). 2024. PMID: 38504093 Free PMC article.
Unveiling the multifaceted landscape of N-glycosylation in antibody variable domains: Insights and implications.
Melo-Braga MN, Carvalho MB, Ferreira MCE, Lavinder J, Abbasi A, Palmisano G, Thaysen-Andersen M, Sajadi MM, Ippolito GC, Felicori LF. Melo-Braga MN, et al. Among authors: sajadi mm. Int J Biol Macromol. 2024 Feb;257(Pt 1):128362. doi: 10.1016/j.ijbiomac.2023.128362. Epub 2023 Nov 28. Int J Biol Macromol. 2024. PMID: 38029898 Free PMC article.
Aerosol delivery of SARS-CoV-2 human monoclonal antibodies in macaques limits viral replication and lung pathology.
Streblow DN, Hirsch AJ, Stanton JJ, Lewis AD, Colgin L, Hessell AJ, Kreklywich CN, Smith JL, Sutton WF, Chauvin D, Woo J, Bimber BN, LeBlanc CN, Acharya SN, O'Roak BJ, Sardar H, Sajadi MM, Tehrani ZR, Walter MR, Martinez-Sobrido L, Kobie JJ, Reader RJ, Olstad KJ, Hobbs TR, Saphire EO, Schendel SL, Carnahan RH, Knoch J, Branco LM, Crowe JE Jr, Van Rompay KKA, Lovalenti P, Vu Truong, Forthal DN, Haigwood NL. Streblow DN, et al. Among authors: sajadi mm. Nat Commun. 2023 Nov 3;14(1):7062. doi: 10.1038/s41467-023-42440-x. Nat Commun. 2023. PMID: 37923717 Free PMC article.
The molecular basis of the neutralization breadth of the RBD-specific antibody CoV11.
Tolbert WD, Chen Y, Sun L, Benlarbi M, Ding S, Manickam R, Pangaro E, Nguyen DN, Gottumukkala S, Côté M, Gonzalez FJ, Finzi A, Tehrani ZR, Sajadi MM, Pazgier M. Tolbert WD, et al. Among authors: sajadi mm. Front Immunol. 2023 Jun 2;14:1178355. doi: 10.3389/fimmu.2023.1178355. eCollection 2023. Front Immunol. 2023. PMID: 37334379 Free PMC article.
Early Elevated IFNα Identified as the Key Mediator of HIV Pathogenesis and its low level a Hallmark of Elite Controllers.
Le Buanec H, Schiavon V, Merandet M, How-Kit A, Bergerat D, Fombellida-Lopez C, Bensussan A, Bouaziz JD, Burny A, Darcis G, Song H, Sajadi MM, Kottilil S, Gallo RC, Zagury D. Le Buanec H, et al. Among authors: sajadi mm. Res Sq [Preprint]. 2023 May 11:rs.3.rs-2813601. doi: 10.21203/rs.3.rs-2813601/v1. Res Sq. 2023. PMID: 37215045 Free PMC article. Updated. Preprint.
IFNα induces CCR5 in CD4+ T-cells, causing its anti- HIV inefficiency and its subsequent pathogenic elevation, partially controlled by anti-HIV therapy.
Le Buanec H, Schiavon V, Merandet M, How-Kit A, Song H, Bergerat D, Fombellida-Lopez C, Bensussan A, Bouaziz JD, Burny A, Darcis G, Sajadi MM, Kottilil S, Zagury D, Gallo RC. Le Buanec H, et al. Among authors: sajadi mm. Res Sq [Preprint]. 2023 May 11:rs.3.rs-2813616. doi: 10.21203/rs.3.rs-2813616/v1. Res Sq. 2023. PMID: 37214795 Free PMC article. Updated. Preprint.
83 results