Saito H - Search Results

1

Vitamin D analogs and bone: preclinical and clinical studies with eldecalcitol.

Matsumoto T, Takano T, Saito H, Takahashi F. Matsumoto T, et al. Among authors: saito h. Bonekey Rep. 2014 Mar 5;3:513. doi: 10.1038/bonekey.2014.8. eCollection 2014. Bonekey Rep. 2014. PMID: 24818005 Free PMC article. Review.

2

Synthesis and evaluation of a 3-position diastereomer of 1alpha,25-dihydroxy-2beta-(3-hydroxypropoxy)vitamin D3 (ED-71).

Hatakeyama S, Nagashima S, Imai N, Takahashi K, Ishihara J, Sugita A, Nihei T, Saito H, Takahashi F, Kubodera N. Hatakeyama S, et al. Among authors: saito h. Bioorg Med Chem. 2006 Dec 1;14(23):8050-6. doi: 10.1016/j.bmc.2006.07.039. Bioorg Med Chem. 2006. PMID: 16908172

3

Synthesis and biological evaluation of a 3-positon epimer of 1alpha,25-dihydroxy-2beta-(3-hydroxypropoxy)vitamin D3 (ED-71).

Hatakeyama S, Nagashima S, Imai N, Takahashi K, Ishihara J, Sugita A, Nihei T, Saito H, Takahashi F, Kubodera N. Hatakeyama S, et al. Among authors: saito h. J Steroid Biochem Mol Biol. 2007 Mar;103(3-5):222-6. doi: 10.1016/j.jsbmb.2006.12.025. Epub 2007 Jan 5. J Steroid Biochem Mol Biol. 2007. PMID: 17207991

4

Eldecalcitol is less effective in suppressing parathyroid hormone compared to calcitriol in vivo.

Harada S, Takeda S, Uno A, Takahashi F, Saito H. Harada S, et al. Among authors: saito h. J Steroid Biochem Mol Biol. 2010 Jul;121(1-2):281-3. doi: 10.1016/j.jsbmb.2010.04.001. Epub 2010 Apr 14. J Steroid Biochem Mol Biol. 2010. PMID: 20398764

5

Daily administration of eldecalcitol (ED-71), an active vitamin D analog, increases bone mineral density by suppressing RANKL expression in mouse trabecular bone.

Harada S, Mizoguchi T, Kobayashi Y, Nakamichi Y, Takeda S, Sakai S, Takahashi F, Saito H, Yasuda H, Udagawa N, Suda T, Takahashi N. Harada S, et al. Among authors: saito h. J Bone Miner Res. 2012 Feb;27(2):461-73. doi: 10.1002/jbmr.555. J Bone Miner Res. 2012. PMID: 22052469 Free article.

6

Eldecalcitol normalizes bone turnover markers regardless of their pre-treatment levels.

Shiraki M, Saito H, Matsumoto T. Shiraki M, et al. Among authors: saito h. Curr Med Res Opin. 2012 Sep;28(9):1547-52. doi: 10.1185/03007995.2012.712506. Epub 2012 Aug 23. Curr Med Res Opin. 2012. PMID: 22794117 Clinical Trial.

7

Eldecalcitol and calcitriol stimulates 'bone minimodeling,' focal bone formation without prior bone resorption, in rat trabecular bone.

Saito H, Takeda S, Amizuka N. Saito H, et al. J Steroid Biochem Mol Biol. 2013 Jul;136:178-82. doi: 10.1016/j.jsbmb.2012.10.004. Epub 2012 Oct 13. J Steroid Biochem Mol Biol. 2013. PMID: 23069645 Review.

8

Eldecalcitol improves mechanical strength of cortical bones by stimulating the periosteal bone formation in the senescence-accelerated SAM/P6 mice - a comparison with alfacalcidol.

Shiraishi A, Sakai S, Saito H, Takahashi F. Shiraishi A, et al. Among authors: saito h. J Steroid Biochem Mol Biol. 2014 Oct;144 Pt A:119-23. doi: 10.1016/j.jsbmb.2013.10.024. Epub 2013 Nov 1. J Steroid Biochem Mol Biol. 2014. PMID: 24189542 Review.

9

Relationship between the effect of eldecalcitol and serum 25(OH)D level.

Takano T, Kondo S, Saito H, Matsumoto T; Eldecalcitol Study Group. Takano T, et al. Among authors: saito h. J Steroid Biochem Mol Biol. 2014 Oct;144 Pt A:124-7. doi: 10.1016/j.jsbmb.2013.11.005. Epub 2013 Nov 15. J Steroid Biochem Mol Biol. 2014. PMID: 24240066 Free article.

10

Long-term treatment with eldecalcitol (1α, 25-dihydroxy-2β- (3-hydroxypropyloxy) vitamin D3) suppresses bone turnover and leads to prevention of bone loss and bone fragility in ovariectomized rats.

Takeda S, Smith SY, Tamura T, Saito H, Takahashi F, Samadfam R, Haile S, Doyle N, Endo K. Takeda S, et al. Among authors: saito h. Calcif Tissue Int. 2015 Jan;96(1):45-55. doi: 10.1007/s00223-014-9937-5. Epub 2014 Dec 4. Calcif Tissue Int. 2015. PMID: 25467010

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