Saintomé C - Search Results

1

Gain-of-function mutations in RPA1 cause a syndrome with short telomeres and somatic genetic rescue.

Sharma R, Sahoo SS, Honda M, Granger SL, Goodings C, Sanchez L, Künstner A, Busch H, Beier F, Pruett-Miller SM, Valentine MB, Fernandez AG, Chang TC, Géli V, Churikov D, Hirschi S, Pastor VB, Boerries M, Lauten M, Kelaidi C, Cooper MA, Nicholas S, Rosenfeld JA, Polychronopoulou S, Kannengiesser C, Saintomé C, Niemeyer CM, Revy P, Wold MS, Spies M, Erlacher M, Coulon S, Wlodarski MW. Sharma R, et al. Among authors: saintome c. Blood. 2022 Feb 17;139(7):1039-1051. doi: 10.1182/blood.2021011980. Blood. 2022. PMID: 34767620 Free PMC article.

2

RPA prevents G-rich structure formation at lagging-strand telomeres to allow maintenance of chromosome ends.

Audry J, Maestroni L, Delagoutte E, Gauthier T, Nakamura TM, Gachet Y, Saintomé C, Géli V, Coulon S. Audry J, et al. Among authors: saintome c. EMBO J. 2015 Jul 14;34(14):1942-58. doi: 10.15252/embj.201490773. Epub 2015 Jun 3. EMBO J. 2015. PMID: 26041456 Free PMC article.

3

The binding efficiency of RPA to telomeric G-strands folded into contiguous G-quadruplexes is independent of the number of G4 units.

Lancrey A, Safa L, Chatain J, Delagoutte E, Riou JF, Alberti P, Saintomé C. Lancrey A, et al. Among authors: saintome c. Biochimie. 2018 Mar;146:68-72. doi: 10.1016/j.biochi.2017.11.017. Epub 2017 Nov 29. Biochimie. 2018. PMID: 29191792

4

Photoactivatable oligonucleotide probes to trap single-stranded DNA binding proteins: Updating the potential of 4-thiothymidine from a comparative study.

Gérard-Hirne T, Thiebaut F, Sachon E, Désert A, Drujon T, Guérineau V, Michel BY, Benhida R, Coulon S, Saintomé C, Guianvarc'h D. Gérard-Hirne T, et al. Among authors: saintome c. Biochimie. 2018 Nov;154:164-175. doi: 10.1016/j.biochi.2018.08.007. Epub 2018 Aug 29. Biochimie. 2018. PMID: 30171884

5

Binding polarity of RPA to telomeric sequences and influence of G-quadruplex stability.

Safa L, Delagoutte E, Petruseva I, Alberti P, Lavrik O, Riou JF, Saintomé C. Safa L, et al. Among authors: saintome c. Biochimie. 2014 Aug;103:80-8. doi: 10.1016/j.biochi.2014.04.006. Epub 2014 Apr 18. Biochimie. 2014. PMID: 24747047

6

5' to 3' Unfolding Directionality of DNA Secondary Structures by Replication Protein A: G-QUADRUPLEXES AND DUPLEXES.

Safa L, Gueddouda NM, Thiébaut F, Delagoutte E, Petruseva I, Lavrik O, Mendoza O, Bourdoncle A, Alberti P, Riou JF, Saintomé C. Safa L, et al. Among authors: saintome c. J Biol Chem. 2016 Sep 30;291(40):21246-21256. doi: 10.1074/jbc.M115.709667. Epub 2016 Jul 19. J Biol Chem. 2016. PMID: 27440048 Free PMC article.

7

Functional Diversification of Replication Protein A Paralogs and Telomere Length Maintenance in Arabidopsis.

Aklilu BB, Peurois F, Saintomé C, Culligan KM, Kobbe D, Leasure C, Chung M, Cattoor M, Lynch R, Sampson L, Fatora J, Shippen DE. Aklilu BB, et al. Among authors: saintome c. Genetics. 2020 Aug;215(4):989-1002. doi: 10.1534/genetics.120.303222. Epub 2020 Jun 12. Genetics. 2020. PMID: 32532801 Free PMC article.

8

GGGCTA repeats can fold into hairpins poorly unfolded by replication protein A: a possible origin of the length-dependent instability of GGGCTA variant repeats in human telomeres.

Chatain J, Blond A, Phan AT, Saintomé C, Alberti P. Chatain J, et al. Among authors: saintome c. Nucleic Acids Res. 2021 Jul 21;49(13):7588-7601. doi: 10.1093/nar/gkab518. Nucleic Acids Res. 2021. PMID: 34214172 Free PMC article.

9

Multiple hPOT1-TPP1 cooperatively unfold contiguous telomeric G-quadruplexes proceeding from 3' toward 5', a feature due to a 3'-end binding preference and to structuring of telomeric DNA.

Chatain J, Hatem G, Delagoutte E, Riou JF, Alberti P, Saintomé C. Chatain J, et al. Among authors: saintome c. Nucleic Acids Res. 2021 Oct 11;49(18):10735-10746. doi: 10.1093/nar/gkab768. Nucleic Acids Res. 2021. PMID: 34534331 Free PMC article.

10

A multi-approach analysis highlights the relevance of RPA-1 as a telomere end-binding protein (TEBP) in Leishmania amazonensis.

Fernandes CAH, Morea EGO, Dos Santos GA, da Silva VL, Vieira MR, Viviescas MA, Chatain J, Vadel A, Saintomé C, Fontes MRM, Cano MIN. Fernandes CAH, et al. Among authors: saintome c. Biochim Biophys Acta Gen Subj. 2020 Jul;1864(7):129607. doi: 10.1016/j.bbagen.2020.129607. Epub 2020 Mar 25. Biochim Biophys Acta Gen Subj. 2020. PMID: 32222548

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