Saini N - Search Results

1

Genome-wide screen identifies pathways that govern GAA/TTC repeat fragility and expansions in dividing and nondividing yeast cells.

Zhang Y, Shishkin AA, Nishida Y, Marcinkowski-Desmond D, Saini N, Volkov KV, Mirkin SM, Lobachev KS. Zhang Y, et al. Among authors: saini n. Mol Cell. 2012 Oct 26;48(2):254-65. doi: 10.1016/j.molcel.2012.08.002. Epub 2012 Sep 6. Mol Cell. 2012. PMID: 22959270 Free PMC article.

2

When secondary comes first--the importance of non-canonical DNA structures.

Saini N, Zhang Y, Usdin K, Lobachev KS. Saini N, et al. Biochimie. 2013 Feb;95(2):117-23. doi: 10.1016/j.biochi.2012.10.005. Epub 2012 Oct 16. Biochimie. 2013. PMID: 23084930 Free PMC article.

3

Fragile DNA motifs trigger mutagenesis at distant chromosomal loci in saccharomyces cerevisiae.

Saini N, Zhang Y, Nishida Y, Sheng Z, Choudhury S, Mieczkowski P, Lobachev KS. Saini N, et al. PLoS Genet. 2013 Jun;9(6):e1003551. doi: 10.1371/journal.pgen.1003551. Epub 2013 Jun 13. PLoS Genet. 2013. PMID: 23785298 Free PMC article.

4

Migrating bubble during break-induced replication drives conservative DNA synthesis.

Saini N, Ramakrishnan S, Elango R, Ayyar S, Zhang Y, Deem A, Ira G, Haber JE, Lobachev KS, Malkova A. Saini N, et al. Nature. 2013 Oct 17;502(7471):389-92. doi: 10.1038/nature12584. Epub 2013 Sep 11. Nature. 2013. PMID: 24025772 Free PMC article.

5

Genome-wide screen reveals replication pathway for quasi-palindrome fragility dependent on homologous recombination.

Zhang Y, Saini N, Sheng Z, Lobachev KS. Zhang Y, et al. Among authors: saini n. PLoS Genet. 2013;9(12):e1003979. doi: 10.1371/journal.pgen.1003979. Epub 2013 Dec 5. PLoS Genet. 2013. PMID: 24339793 Free PMC article.

6

Somatic mutation load and spectra: A record of DNA damage and repair in healthy human cells.

Saini N, Gordenin DA. Saini N, et al. Environ Mol Mutagen. 2018 Oct;59(8):672-686. doi: 10.1002/em.22215. Epub 2018 Aug 27. Environ Mol Mutagen. 2018. PMID: 30152078 Free PMC article. Review.

7

An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers.

Chan K, Roberts SA, Klimczak LJ, Sterling JF, Saini N, Malc EP, Kim J, Kwiatkowski DJ, Fargo DC, Mieczkowski PA, Getz G, Gordenin DA. Chan K, et al. Among authors: saini n. Nat Genet. 2015 Sep;47(9):1067-72. doi: 10.1038/ng.3378. Epub 2015 Aug 10. Nat Genet. 2015. PMID: 26258849 Free PMC article.

8

The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts.

Saini N, Roberts SA, Klimczak LJ, Chan K, Grimm SA, Dai S, Fargo DC, Boyer JC, Kaufmann WK, Taylor JA, Lee E, Cortes-Ciriano I, Park PJ, Schurman SH, Malc EP, Mieczkowski PA, Gordenin DA. Saini N, et al. PLoS Genet. 2016 Oct 27;12(10):e1006385. doi: 10.1371/journal.pgen.1006385. eCollection 2016 Oct. PLoS Genet. 2016. PMID: 27788131 Free PMC article. Clinical Trial.

9

APOBEC3B cytidine deaminase targets the non-transcribed strand of tRNA genes in yeast.

Saini N, Roberts SA, Sterling JF, Malc EP, Mieczkowski PA, Gordenin DA. Saini N, et al. DNA Repair (Amst). 2017 May;53:4-14. doi: 10.1016/j.dnarep.2017.03.003. Epub 2017 Mar 21. DNA Repair (Amst). 2017. PMID: 28351647 Free PMC article.

10

Corrigendum to "APOBEC3B cytidine deaminase targets the non-transcribed strand of tRNA genes in yeast" [DNA Repair 53 (2017) 4-14].

Saini N, Roberts SA, Sterling JF, Malc EP, Mieczkowski PA, Gordenin DA. Saini N, et al. DNA Repair (Amst). 2019 Aug;80:94-95. doi: 10.1016/j.dnarep.2019.05.006. Epub 2019 Jun 7. DNA Repair (Amst). 2019. PMID: 31182349 No abstract available.

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