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Programmable Molecular Scissors: Applications of a New Tool for Genome Editing in Biotech.
Mol Ther Nucleic Acids. 2019 Mar 1;14:212-238. doi: 10.1016/j.omtn.2018.11.016. Epub 2018 Dec 6.
Mol Ther Nucleic Acids. 2019.
PMID: 30641475
Free PMC article.
Review.
Function of the SIRT3 mitochondrial deacetylase in cellular physiology, cancer, and neurodegenerative disease.
Ansari A, Rahman MS, Saha SK, Saikot FK, Deep A, Kim KH.
Ansari A, et al. Among authors: saikot fk.
Aging Cell. 2017 Feb;16(1):4-16. doi: 10.1111/acel.12538. Epub 2016 Sep 29.
Aging Cell. 2017.
PMID: 27686535
Free PMC article.
Review.
Item in Clipboard
Structural basis of SARM1 activation, substrate recognition, and inhibition by small molecules.
Shi Y, Kerry PS, Nanson JD, Bosanac T, Sasaki Y, Krauss R, Saikot FK, Adams SE, Mosaiab T, Masic V, Mao X, Rose F, Vasquez E, Furrer M, Cunnea K, Brearley A, Gu W, Luo Z, Brillault L, Landsberg MJ, DiAntonio A, Kobe B, Milbrandt J, Hughes RO, Ve T.
Shi Y, et al. Among authors: saikot fk.
Mol Cell. 2022 May 5;82(9):1643-1659.e10. doi: 10.1016/j.molcel.2022.03.007. Epub 2022 Mar 24.
Mol Cell. 2022.
PMID: 35334231
Free PMC article.
Item in Clipboard
Structural Evolution of TIR-Domain Signalosomes.
Nimma S, Gu W, Maruta N, Li Y, Pan M, Saikot FK, Lim BYJ, McGuinness HY, Zaoti ZF, Li S, Desa S, Manik MK, Nanson JD, Kobe B.
Nimma S, et al. Among authors: saikot fk.
Front Immunol. 2021 Nov 17;12:784484. doi: 10.3389/fimmu.2021.784484. eCollection 2021.
Front Immunol. 2021.
PMID: 34868065
Free PMC article.
Review.
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SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration.
Figley MD, Gu W, Nanson JD, Shi Y, Sasaki Y, Cunnea K, Malde AK, Jia X, Luo Z, Saikot FK, Mosaiab T, Masic V, Holt S, Hartley-Tassell L, McGuinness HY, Manik MK, Bosanac T, Landsberg MJ, Kerry PS, Mobli M, Hughes RO, Milbrandt J, Kobe B, DiAntonio A, Ve T.
Figley MD, et al. Among authors: saikot fk.
Neuron. 2021 Apr 7;109(7):1118-1136.e11. doi: 10.1016/j.neuron.2021.02.009. Epub 2021 Mar 2.
Neuron. 2021.
PMID: 33657413
Free PMC article.
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