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Acetylsalicylic Acid Suppresses Alcoholism-Induced Cognitive Impairment Associated with Atorvastatin Intake by Targeting Cerebral miRNA155 and NLRP3: In Vivo, and In Silico Study.
Mohamed DI, Alaa El-Din Aly El-Waseef D, Nabih ES, El-Kharashi OA, Abd El-Kareem HF, Abo Nahas HH, Abdel-Wahab BA, Helmy YA, Alshawwa SZ, Saied EM. Mohamed DI, et al. Among authors: saied em. Pharmaceutics. 2022 Feb 27;14(3):529. doi: 10.3390/pharmaceutics14030529. Pharmaceutics. 2022. PMID: 35335908 Free PMC article.
Hepatoprotective Role of Carvedilol against Ischemic Hepatitis Associated with Acute Heart Failure via Targeting miRNA-17 and Mitochondrial Dynamics-Related Proteins: An In Vivo and In Silico Study.
Mohamed DI, Ezzat SF, Elayat WM, El-Kharashi OA, El-Kareem HFA, Nahas HHA, Abdel-Wahab BA, Alshawwa SZ, Saleh A, Helmy YA, Khairy E, Saied EM. Mohamed DI, et al. Among authors: saied em. Pharmaceuticals (Basel). 2022 Jul 5;15(7):832. doi: 10.3390/ph15070832. Pharmaceuticals (Basel). 2022. PMID: 35890131 Free PMC article.
Identification of Small-Molecule Inhibitors of Neutral Ceramidase (nCDase) via Target-Based High-Throughput Screening.
Otsuka Y, Airola MV, Choi YM, Coant N, Snider J, Cariello C, Saied EM, Arenz C, Bannister T, Rahaim R Jr, Hannun YA, Shumate J, Scampavia L, Haley JD, Spicer TP. Otsuka Y, et al. Among authors: saied em. SLAS Discov. 2021 Jan;26(1):113-121. doi: 10.1177/2472555220945283. Epub 2020 Jul 31. SLAS Discov. 2021. PMID: 32734807 Free PMC article.
Discovery and Mechanism of Action of Small Molecule Inhibitors of Ceramidases.
Healey RD, Saied EM, Cong X, Karsai G, Gabellier L, Saint-Paul J, Del Nero E, Jeannot S, Drapeau M, Fontanel S, Maurel D, Basu S, Leyrat C, Golebiowski J, Bossis G, Bechara C, Hornemann T, Arenz C, Granier S. Healey RD, et al. Among authors: saied em. Angew Chem Int Ed Engl. 2022 Jan 10;61(2):e202109967. doi: 10.1002/anie.202109967. Epub 2021 Nov 25. Angew Chem Int Ed Engl. 2022. PMID: 34668624
Novel 2-substituted-quinoxaline analogs with potential antiproliferative activity against breast cancer: insights into cell cycle arrest, topoisomerase II, and EGFR activity.
Salem MG, Abu El-Ata SA, Elsayed EH, Mali SN, Alshwyeh HA, Almaimani G, Almaimani RA, Almasmoum HA, Altwaijry N, Al-Olayan E, Saied EM, Youssef MF. Salem MG, et al. Among authors: saied em. RSC Adv. 2023 Nov 9;13(47):33080-33095. doi: 10.1039/d3ra06189b. eCollection 2023 Nov 7. RSC Adv. 2023. PMID: 37954422 Free PMC article.
74 results