Saiardi A - Search Results

1

The Effect of Inositol Hexakisphosphate on HIV-1 Particle Production and Infectivity can be Modulated by Mutations that Affect the Stability of the Immature Gag Lattice.

Kleinpeter AB, Zhu Y, Mallery DL, Ablan SD, Chen L, Hardenbrook N, Saiardi A, James LC, Zhang P, Freed EO. Kleinpeter AB, et al. Among authors: saiardi a. J Mol Biol. 2023 Jun 1;435(11):168037. doi: 10.1016/j.jmb.2023.168037. Epub 2023 Jun 16. J Mol Biol. 2023. PMID: 37330292

2

HIV-1 is dependent on its immature lattice to recruit IP6 for mature capsid assembly.

Renner N, Kleinpeter A, Mallery DL, Albecka A, Rifat Faysal KM, Böcking T, Saiardi A, Freed EO, James LC. Renner N, et al. Among authors: saiardi a. Nat Struct Mol Biol. 2023 Mar;30(3):370-382. doi: 10.1038/s41594-022-00887-4. Epub 2023 Jan 9. Nat Struct Mol Biol. 2023. PMID: 36624347 Free PMC article.

3

On the covalent nature of lysine polyphosphorylation.

Azevedo C, Borghi F, Su XB, Saiardi A. Azevedo C, et al. Among authors: saiardi a. Mol Cell. 2024 May 2;84(9):1811-1815.e3. doi: 10.1016/j.molcel.2024.03.029. Mol Cell. 2024. PMID: 38701742 Free article.

4

The phytase RipBL1 enables the assignment of a specific inositol phosphate isomer as a structural component of human kidney stones.

Liu G, Riemer E, Schneider R, Cabuzu D, Bonny O, Wagner CA, Qiu D, Saiardi A, Strauss A, Lahaye T, Schaaf G, Knoll T, Jessen JP, Jessen HJ. Liu G, et al. Among authors: saiardi a. RSC Chem Biol. 2023 Jan 27;4(4):300-309. doi: 10.1039/d2cb00235c. eCollection 2023 Apr 5. RSC Chem Biol. 2023. PMID: 37034402 Free PMC article.

5

Inositol pyrophosphate profiling reveals regulatory roles of IP6K2-dependent enhanced IP₇ metabolism in the enteric nervous system.

Ito M, Fujii N, Kohara S, Hori S, Tanaka M, Wittwer C, Kikuchi K, Iijima T, Kakimoto Y, Hirabayashi K, Kurotaki D, Jessen HJ, Saiardi A, Nagata E. Ito M, et al. Among authors: saiardi a. J Biol Chem. 2023 Mar;299(3):102928. doi: 10.1016/j.jbc.2023.102928. Epub 2023 Jan 19. J Biol Chem. 2023. PMID: 36681123 Free PMC article.

6

The Ip6k1 and Ip6k2 Kinases Are Critical for Normal Renal Tubular Function.

Haykir B, Moser SO, Pastor-Arroyo EM, Schnitzbauer U, Radvanyi Z, Prucker I, Qiu D, Fiedler D, Saiardi A, Jessen HJ, Hernando N, Wagner CA. Haykir B, et al. Among authors: saiardi a. J Am Soc Nephrol. 2024 Apr 1;35(4):441-455. doi: 10.1681/ASN.0000000000000303. Epub 2024 Feb 6. J Am Soc Nephrol. 2024. PMID: 38317282

7

Biochemical and structural characterization of an inositol pyrophosphate kinase from a giant virus.

Zong G, Desfougères Y, Portela-Torres P, Kwon YU, Saiardi A, Shears SB, Wang H. Zong G, et al. Among authors: saiardi a. EMBO J. 2024 Feb;43(3):462-480. doi: 10.1038/s44318-023-00005-0. Epub 2024 Jan 12. EMBO J. 2024. PMID: 38216735 Free PMC article.

8

Evolutionary perspective on mammalian inorganic polyphosphate (polyP) biology.

Borghi F, Saiardi A. Borghi F, et al. Among authors: saiardi a. Biochem Soc Trans. 2023 Oct 31;51(5):1947-1956. doi: 10.1042/BST20230483. Biochem Soc Trans. 2023. PMID: 37844192 Free PMC article. Review.

9

β-lapachone regulates mammalian inositol pyrophosphate levels in an NQO1- and oxygen-dependent manner.

Eisenbeis VB, Qiu D, Gorka O, Strotmann L, Liu G, Prucker I, Su XB, Wilson MSC, Ritter K, Loenarz C, Groß O, Saiardi A, Jessen HJ. Eisenbeis VB, et al. Among authors: saiardi a. Proc Natl Acad Sci U S A. 2023 Aug 22;120(34):e2306868120. doi: 10.1073/pnas.2306868120. Epub 2023 Aug 14. Proc Natl Acad Sci U S A. 2023. PMID: 37579180 Free PMC article.

10

Stable Isotopomers of myo-Inositol Uncover a Complex MINPP1-Dependent Inositol Phosphate Network.

Nguyen Trung M, Kieninger S, Fandi Z, Qiu D, Liu G, Mehendale NK, Saiardi A, Jessen H, Keller B, Fiedler D. Nguyen Trung M, et al. Among authors: saiardi a. ACS Cent Sci. 2022 Dec 28;8(12):1683-1694. doi: 10.1021/acscentsci.2c01032. Epub 2022 Dec 5. ACS Cent Sci. 2022. PMID: 36589890 Free PMC article.

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