Sahlholm K - Search Results

1

Major Genetic Risk Factors for Dupuytren's Disease Are Inherited From Neandertals.

Ågren R, Patil S, Zhou X; FinnGen.; Sahlholm K, Pääbo S, Zeberg H. Ågren R, et al. Among authors: sahlholm k. Mol Biol Evol. 2023 Jun 1;40(6):msad130. doi: 10.1093/molbev/msad130. Mol Biol Evol. 2023. PMID: 37315093 Free PMC article.

2

The fast-off hypothesis revisited: A functional kinetic study of antipsychotic antagonism of the dopamine D2 receptor.

Sahlholm K, Zeberg H, Nilsson J, Ögren SO, Fuxe K, Århem P. Sahlholm K, et al. Eur Neuropsychopharmacol. 2016 Mar;26(3):467-76. doi: 10.1016/j.euroneuro.2016.01.001. Epub 2016 Jan 14. Eur Neuropsychopharmacol. 2016. PMID: 26811292

3

Point mutation of a conserved aspartate, D69, in the muscarinic M₂ receptor does not modify voltage-sensitive agonist potency.

Ågren R, Sahlholm K, Nilsson J, Århem P. Ågren R, et al. Among authors: sahlholm k. Biochem Biophys Res Commun. 2018 Jan 29;496(1):101-104. doi: 10.1016/j.bbrc.2018.01.005. Epub 2018 Jan 2. Biochem Biophys Res Commun. 2018. PMID: 29305262

4

The Beta-Arrestin-Biased Dopamine D2 Receptor Ligand, UNC9994, Is a Partial Agonist at G-Protein-Mediated Potassium Channel Activation.

Ågren R, Århem P, Nilsson J, Sahlholm K. Ågren R, et al. Among authors: sahlholm k. Int J Neuropsychopharmacol. 2018 Dec 1;21(12):1102-1108. doi: 10.1093/ijnp/pyy059. Int J Neuropsychopharmacol. 2018. PMID: 29986044 Free PMC article.

5

Antipsychotics with similar association kinetics at dopamine D₂ receptors differ in extrapyramidal side-effects.

Zeberg H, Sahlholm K. Zeberg H, et al. Among authors: sahlholm k. Nat Commun. 2018 Sep 3;9(1):3577. doi: 10.1038/s41467-018-04489-x. Nat Commun. 2018. PMID: 30177830 Free PMC article. No abstract available.

6

A Neanderthal Sodium Channel Increases Pain Sensitivity in Present-Day Humans.

Zeberg H, Dannemann M, Sahlholm K, Tsuo K, Maricic T, Wiebe V, Hevers W, Robinson HPC, Kelso J, Pääbo S. Zeberg H, et al. Among authors: sahlholm k. Curr Biol. 2020 Sep 7;30(17):3465-3469.e4. doi: 10.1016/j.cub.2020.06.045. Epub 2020 Jul 23. Curr Biol. 2020. PMID: 32707058 Free article.

7

Ligand with Two Modes of Interaction with the Dopamine D₂ Receptor-An Induced-Fit Mechanism of Insurmountable Antagonism.

Ågren R, Zeberg H, Stępniewski TM, Free RB, Reilly SW, Luedtke RR, Århem P, Ciruela F, Sibley DR, Mach RH, Selent J, Nilsson J, Sahlholm K. Ågren R, et al. Among authors: sahlholm k. ACS Chem Neurosci. 2020 Oct 7;11(19):3130-3143. doi: 10.1021/acschemneuro.0c00477. Epub 2020 Sep 15. ACS Chem Neurosci. 2020. PMID: 32865974 Free PMC article.

8

Voltage-Dependent Dopamine Potency at D₁-Like Dopamine Receptors.

Ågren R, Sahlholm K. Ågren R, et al. Among authors: sahlholm k. Front Pharmacol. 2020 Oct 7;11:581151. doi: 10.3389/fphar.2020.581151. eCollection 2020. Front Pharmacol. 2020. PMID: 33117177 Free PMC article.

9

Dopamine D₂ Receptor Agonist Binding Kinetics-Role of a Conserved Serine Residue.

Ågren R, Stepniewski TM, Zeberg H, Selent J, Sahlholm K. Ågren R, et al. Among authors: sahlholm k. Int J Mol Sci. 2021 Apr 15;22(8):4078. doi: 10.3390/ijms22084078. Int J Mol Sci. 2021. PMID: 33920848 Free PMC article.

10

G protein-coupled receptor kinase-2 confers isoform-specific calcium sensitivity to dopamine D₂ receptor desensitization.

Ågren R, Sahlholm K. Ågren R, et al. Among authors: sahlholm k. FASEB J. 2021 Nov;35(11):e22013. doi: 10.1096/fj.202100704RR. FASEB J. 2021. PMID: 34699610

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