Sahlholm K - Search Results

1

Correction To: TAAR1 dependent and independent actions of the potential antipsychotic and dual TAAR1/5-HT_1A receptor agonist SEP- 363856.

Saarinen M, Mantas I, Flais I, Ågren R, Sahlholm K, Millan MJ, Svenningsson P. Saarinen M, et al. Among authors: sahlholm k. Neuropsychopharmacology. 2023 Apr;48(5):846. doi: 10.1038/s41386-022-01504-0. Neuropsychopharmacology. 2023. PMID: 36446929 Free PMC article. No abstract available.

2

Point mutation of a conserved aspartate, D69, in the muscarinic M₂ receptor does not modify voltage-sensitive agonist potency.

Ågren R, Sahlholm K, Nilsson J, Århem P. Ågren R, et al. Among authors: sahlholm k. Biochem Biophys Res Commun. 2018 Jan 29;496(1):101-104. doi: 10.1016/j.bbrc.2018.01.005. Epub 2018 Jan 2. Biochem Biophys Res Commun. 2018. PMID: 29305262

3

The Beta-Arrestin-Biased Dopamine D2 Receptor Ligand, UNC9994, Is a Partial Agonist at G-Protein-Mediated Potassium Channel Activation.

Ågren R, Århem P, Nilsson J, Sahlholm K. Ågren R, et al. Among authors: sahlholm k. Int J Neuropsychopharmacol. 2018 Dec 1;21(12):1102-1108. doi: 10.1093/ijnp/pyy059. Int J Neuropsychopharmacol. 2018. PMID: 29986044 Free PMC article.

4

Ligand with Two Modes of Interaction with the Dopamine D₂ Receptor-An Induced-Fit Mechanism of Insurmountable Antagonism.

Ågren R, Zeberg H, Stępniewski TM, Free RB, Reilly SW, Luedtke RR, Århem P, Ciruela F, Sibley DR, Mach RH, Selent J, Nilsson J, Sahlholm K. Ågren R, et al. Among authors: sahlholm k. ACS Chem Neurosci. 2020 Oct 7;11(19):3130-3143. doi: 10.1021/acschemneuro.0c00477. Epub 2020 Sep 15. ACS Chem Neurosci. 2020. PMID: 32865974 Free PMC article.

5

Voltage-Dependent Dopamine Potency at D₁-Like Dopamine Receptors.

Ågren R, Sahlholm K. Ågren R, et al. Among authors: sahlholm k. Front Pharmacol. 2020 Oct 7;11:581151. doi: 10.3389/fphar.2020.581151. eCollection 2020. Front Pharmacol. 2020. PMID: 33117177 Free PMC article.

6

V374A KCND3 Pathogenic Variant Associated With Paroxysmal Ataxia Exacerbations.

Paucar M, Ågren R, Li T, Lissmats S, Bergendal Å, Weinberg J, Nilsson D, Savichetva I, Sahlholm K, Nilsson J, Svenningsson P. Paucar M, et al. Among authors: sahlholm k. Neurol Genet. 2021 Jan 6;7(1):e546. doi: 10.1212/NXG.0000000000000546. eCollection 2021 Feb. Neurol Genet. 2021. PMID: 33575485 Free PMC article.

7

Dopamine D₂ Receptor Agonist Binding Kinetics-Role of a Conserved Serine Residue.

Ågren R, Stepniewski TM, Zeberg H, Selent J, Sahlholm K. Ågren R, et al. Among authors: sahlholm k. Int J Mol Sci. 2021 Apr 15;22(8):4078. doi: 10.3390/ijms22084078. Int J Mol Sci. 2021. PMID: 33920848 Free PMC article.

8

Mechanistic insights into dopaminergic and serotonergic neurotransmission - concerted interactions with helices 5 and 6 drive the functional outcome.

Stepniewski TM, Mancini A, Ågren R, Torrens-Fontanals M, Semache M, Bouvier M, Sahlholm K, Breton B, Selent J. Stepniewski TM, et al. Among authors: sahlholm k. Chem Sci. 2021 Jul 2;12(33):10990-11003. doi: 10.1039/d1sc00749a. eCollection 2021 Aug 25. Chem Sci. 2021. PMID: 34522296 Free PMC article.

9

G protein-coupled receptor kinase-2 confers isoform-specific calcium sensitivity to dopamine D₂ receptor desensitization.

Ågren R, Sahlholm K. Ågren R, et al. Among authors: sahlholm k. FASEB J. 2021 Nov;35(11):e22013. doi: 10.1096/fj.202100704RR. FASEB J. 2021. PMID: 34699610

10

Evidence for Two Modes of Binding of the Negative Allosteric Modulator SB269,652 to the Dopamine D₂ Receptor.

Ågren R, Sahlholm K. Ågren R, et al. Among authors: sahlholm k. Biomedicines. 2021 Dec 23;10(1):22. doi: 10.3390/biomedicines10010022. Biomedicines. 2021. PMID: 35052702 Free PMC article.

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