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Synthetic mRNAs with superior translation and stability properties.
Grudzien-Nogalska E, Kowalska J, Su W, Kuhn AN, Slepenkov SV, Darzynkiewicz E, Sahin U, Jemielity J, Rhoads RE. Grudzien-Nogalska E, et al. Among authors: sahin u. Methods Mol Biol. 2013;969:55-72. doi: 10.1007/978-1-62703-260-5_4. Methods Mol Biol. 2013. PMID: 23296927 Review.
Synthesis, properties, and biological activity of boranophosphate analogs of the mRNA cap: versatile tools for manipulation of therapeutically relevant cap-dependent processes.
Kowalska J, Wypijewska del Nogal A, Darzynkiewicz ZM, Buck J, Nicola C, Kuhn AN, Lukaszewicz M, Zuberek J, Strenkowska M, Ziemniak M, Maciejczyk M, Bojarska E, Rhoads RE, Darzynkiewicz E, Sahin U, Jemielity J. Kowalska J, et al. Among authors: sahin u. Nucleic Acids Res. 2014;42(16):10245-64. doi: 10.1093/nar/gku757. Epub 2014 Aug 22. Nucleic Acids Res. 2014. PMID: 25150148 Free PMC article.
mRNA as a versatile tool for exogenous protein expression.
Kuhn AN, Beiβert T, Simon P, Vallazza B, Buck J, Davies BP, Tureci O, Sahin U. Kuhn AN, et al. Among authors: sahin u. Curr Gene Ther. 2012 Oct;12(5):347-61. doi: 10.2174/156652312802762536. Curr Gene Ther. 2012. PMID: 22827224 Review.
Monitoring Translation Activity of mRNA-Loaded Nanoparticles in Mice.
Rosigkeit S, Meng M, Grunwitz C, Gomes P, Kreft A, Hayduk N, Heck R, Pickert G, Ziegler K, Abassi Y, Röder J, Kaps L, Vascotto F, Beissert T, Witzel S, Kuhn A, Diken M, Schuppan D, Sahin U, Haas H, Bockamp E. Rosigkeit S, et al. Among authors: sahin u. Mol Pharm. 2018 Sep 4;15(9):3909-3919. doi: 10.1021/acs.molpharmaceut.8b00370. Epub 2018 Aug 9. Mol Pharm. 2018. PMID: 30028629
488 results