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Distribution and metabolism of 14C-sulfoquinovosylacylpropanediol (14C-SQAP) after a single intravenous administration in tumor-bearing mice.
Ruike T, Kanai Y, Iwabata K, Matsumoto Y, Murata H, Ishima M, Ohta K, Oshige M, Katsura S, Kuramochi K, Kamisuki S, Sahara H, Miura M, Sugawara F, Sakaguchi K. Ruike T, et al. Among authors: sahara h. Xenobiotica. 2019 Mar;49(3):346-362. doi: 10.1080/00498254.2018.1448949. Epub 2018 Apr 24. Xenobiotica. 2019. PMID: 29543539
Novel anticancer agent, SQAP, binds to focal adhesion kinase and modulates its activity.
Izaguirre-Carbonell J, Kawakubo H, Murata H, Tanabe A, Takeuchi T, Kusayanagi T, Tsukuda S, Hirakawa T, Iwabata K, Kanai Y, Ohta K, Miura M, Sakaguchi K, Matsunaga S, Sahara H, Kamisuki S, Sugawara F. Izaguirre-Carbonell J, et al. Among authors: sahara h. Sci Rep. 2015 Oct 12;5:15136. doi: 10.1038/srep15136. Sci Rep. 2015. PMID: 26456697 Free PMC article.
SQAP, an acyl sulfoquinovosyl derivative, suppresses expression of histone deacetylase and induces cell death of cancer cells under hypoxic conditions.
Kawakubo H, Kamisuki S, Suzuki K, Izaguirre-Carbonell J, Saito S, Murata H, Tanabe A, Hongo A, Murakami H, Matsunaga S, Sakaguchi K, Sahara H, Sugawara F, Kuramochi K. Kawakubo H, et al. Among authors: sahara h. Biosci Biotechnol Biochem. 2021 Jan 7;85(1):85-91. doi: 10.1093/bbb/zbaa015. Biosci Biotechnol Biochem. 2021. PMID: 33577659
Cyclosporin A associated helicase-like protein facilitates the association of hepatitis C virus RNA polymerase with its cellular cyclophilin B.
Morohashi K, Sahara H, Watashi K, Iwabata K, Sunoki T, Kuramochi K, Takakusagi K, Miyashita H, Sato N, Tanabe A, Shimotohno K, Kobayashi S, Sakaguchi K, Sugawara F. Morohashi K, et al. Among authors: sahara h. PLoS One. 2011 Apr 29;6(4):e18285. doi: 10.1371/journal.pone.0018285. PLoS One. 2011. PMID: 21559518 Free PMC article.
Pyrenocine A induces monopolar spindle formation and suppresses proliferation of cancer cells.
Myobatake Y, Kamisuki S, Tsukuda S, Higashi T, Chinen T, Takemoto K, Hachisuka M, Suzuki Y, Takei M, Tsurukawa Y, Maekawa H, Takeuchi T, Matsunaga TM, Sahara H, Usui T, Matsunaga S, Sugawara F. Myobatake Y, et al. Among authors: sahara h. Bioorg Med Chem. 2019 Dec 1;27(23):115149. doi: 10.1016/j.bmc.2019.115149. Epub 2019 Oct 15. Bioorg Med Chem. 2019. PMID: 31679979
Effects of a new immunosuppressive agent, beta-SQAG9, in swine kidney transplantation.
Tanaka T, Kitamura H, Sahara H, Imai A, Itoh Y, Honma I, Sato E, Kobayashi K, Maeda T, Takenouchi M, Ohta K, Sugawara F, Sakaguchi K, Ando A, Inoko H, Sato N, Tsukamoto T. Tanaka T, et al. Among authors: sahara h. Transpl Immunol. 2007 Jul;18(1):67-71. doi: 10.1016/j.trim.2007.04.004. Epub 2007 May 30. Transpl Immunol. 2007. PMID: 17584605
141 results