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Metixene is an incomplete autophagy inducer in preclinical models of metastatic cancer and brain metastases.
Fares J, Petrosyan E, Kanojia D, Dmello C, Cordero A, Duffy JT, Yeeravalli R, Sahani MH, Zhang P, Rashidi A, Arrieta VA, Ulasov I, Ahmed AU, Miska J, Balyasnikova IV, James CD, Sonabend AM, Heimberger AB, Lesniak MS. Fares J, et al. Among authors: sahani mh. J Clin Invest. 2023 Dec 15;133(24):e161142. doi: 10.1172/JCI161142. J Clin Invest. 2023. PMID: 37847564 Free PMC article.
FIP200 regulates targeting of Atg16L1 to the isolation membrane.
Nishimura T, Kaizuka T, Cadwell K, Sahani MH, Saitoh T, Akira S, Virgin HW, Mizushima N. Nishimura T, et al. Among authors: sahani mh. EMBO Rep. 2013 Mar 1;14(3):284-91. doi: 10.1038/embor.2013.6. Epub 2013 Feb 8. EMBO Rep. 2013. PMID: 23392225 Free PMC article.