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Guide-free Cas9 from pathogenic Campylobacter jejuni bacteria causes severe damage to DNA.
Saha C, Mohanraju P, Stubbs A, Dugar G, Hoogstrate Y, Kremers GJ, van Cappellen WA, Horst-Kreft D, Laffeber C, Lebbink JHG, Bruens S, Gaskin D, Beerens D, Klunder M, Joosten R, Demmers JAA, van Gent D, Mouton JW, van der Spek PJ, van der Oost J, van Baarlen P, Louwen R. Saha C, et al. Sci Adv. 2020 Jun 17;6(25):eaaz4849. doi: 10.1126/sciadv.aaz4849. eCollection 2020 Jun. Sci Adv. 2020. PMID: 32596446 Free PMC article.
CRISPRs in the human genome are differentially expressed between malignant and normal adjacent to tumor tissue.
van Riet J, Saha C, Strepis N, Brouwer RWW, Martens-Uzunova ES, van de Geer WS, Swagemakers SMA, Stubbs A, Halimi Y, Voogd S, Tanmoy AM, Komor MA, Hoogstrate Y, Janssen B, Fijneman RJA, Niknafs YS, Chinnaiyan AM, van IJcken WFJ, van der Spek PJ, Jenster G, Louwen R. van Riet J, et al. Among authors: saha c. Commun Biol. 2022 Apr 8;5(1):338. doi: 10.1038/s42003-022-03249-4. Commun Biol. 2022. PMID: 35396392 Free PMC article.
255 results