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Establishing the allosteric mechanism in CRISPR-Cas9.
Nierzwicki Ł, Arantes PR, Saha A, Palermo G. Nierzwicki Ł, et al. Among authors: saha a. Wiley Interdiscip Rev Comput Mol Sci. 2021 May-Jun;11(3):e1503. doi: 10.1002/wcms.1503. Epub 2020 Oct 26. Wiley Interdiscip Rev Comput Mol Sci. 2021. PMID: 34322166 Free PMC article.
Fighting COVID-19 Using Molecular Dynamics Simulations.
Arantes PR, Saha A, Palermo G. Arantes PR, et al. Among authors: saha a. ACS Cent Sci. 2020 Oct 28;6(10):1654-1656. doi: 10.1021/acscentsci.0c01236. Epub 2020 Oct 12. ACS Cent Sci. 2020. PMID: 33140032 Free PMC article. No abstract available.
Frontiers of metal-coordinating drug design.
Palermo G, Spinello A, Saha A, Magistrato A. Palermo G, et al. Among authors: saha a. Expert Opin Drug Discov. 2021 May;16(5):497-511. doi: 10.1080/17460441.2021.1851188. Epub 2020 Dec 1. Expert Opin Drug Discov. 2021. PMID: 33874825 Free PMC article. Review.
Enhancement of CRISPR/Cas12a trans-cleavage activity using hairpin DNA reporters.
Rossetti M, Merlo R, Bagheri N, Moscone D, Valenti A, Saha A, Arantes PR, Ippodrino R, Ricci F, Treglia I, Delibato E, van der Oost J, Palermo G, Perugino G, Porchetta A. Rossetti M, et al. Among authors: saha a. Nucleic Acids Res. 2022 Aug 12;50(14):8377-8391. doi: 10.1093/nar/gkac578. Nucleic Acids Res. 2022. PMID: 35822842 Free PMC article.
Structural basis for Cas9 off-target activity.
Pacesa M, Lin CH, Cléry A, Saha A, Arantes PR, Bargsten K, Irby MJ, Allain FH, Palermo G, Cameron P, Donohoue PD, Jinek M. Pacesa M, et al. Among authors: saha a. Cell. 2022 Oct 27;185(22):4067-4081.e21. doi: 10.1016/j.cell.2022.09.026. Cell. 2022. PMID: 36306733 Free PMC article.
2,861 results