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Deciphering the pathogenic role of a variant with uncertain significance for short QT and Brugada syndromes using gene-edited human-induced pluripotent stem cell-derived cardiomyocytes and preclinical drug screening.
El-Battrawy I, Lan H, Cyganek L, Maywald L, Zhong R, Zhang F, Xu Q, Lee J, Duperrex E, Hierlemann A, Saguner AM, Duru F, Kovacs B, Huang M, Liao Z, Albers S, Müller J, Dinkel H, Rose L, Hohn A, Yang Z, Qiao L, Li Y, Lang S, Kleinsorge M, Mügge A, Aweimer A, Fan X, Diecke S, Akin I, Li G, Zhou X. El-Battrawy I, et al. Among authors: saguner am. Clin Transl Med. 2021 Dec;11(12):e646. doi: 10.1002/ctm2.646. Clin Transl Med. 2021. PMID: 34954893 Free PMC article. No abstract available.
Sex hormones affect outcome in arrhythmogenic right ventricular cardiomyopathy/dysplasia: from a stem cell derived cardiomyocyte-based model to clinical biomarkers of disease outcome.
Akdis D, Saguner AM, Shah K, Wei C, Medeiros-Domingo A, von Eckardstein A, Lüscher TF, Brunckhorst C, Chen HSV, Duru F. Akdis D, et al. Among authors: saguner am. Eur Heart J. 2017 May 14;38(19):1498-1508. doi: 10.1093/eurheartj/ehx011. Eur Heart J. 2017. PMID: 28329361 Free PMC article.
221 results