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A Novel and Selective Dopamine Transporter Inhibitor, (S)-MK-26, Promotes Hippocampal Synaptic Plasticity and Restores Effort-Related Motivational Dysfunctions.
Kouhnavardi S, Ecevitoglu A, Dragačević V, Sanna F, Arias-Sandoval E, Kalaba P, Kirchhofer M, Lubec J, Niello M, Holy M, Zehl M, Pillwein M, Wackerlig J, Murau R, Mohrmann A, Beard KR, Sitte HH, Urban E, Sagheddu C, Pistis M, Plasenzotti R, Salamone JD, Langer T, Lubec G, Monje FJ. Kouhnavardi S, et al. Among authors: sagheddu c. Biomolecules. 2022 Jun 24;12(7):881. doi: 10.3390/biom12070881. Biomolecules. 2022. PMID: 35883437 Free PMC article.
Repeated exposure to JWH-018 induces adaptive changes in the mesolimbic and mesocortical dopaminergic pathways, glial cells alterations, and behavioural correlates.
Pintori N, Castelli MP, Miliano C, Simola N, Fadda P, Fattore L, Scherma M, Ennas MG, Mostallino R, Flore G, De Felice M, Sagheddu C, Pistis M, Di Chiara G, De Luca MA. Pintori N, et al. Among authors: sagheddu c. Br J Pharmacol. 2021 Sep;178(17):3476-3497. doi: 10.1111/bph.15494. Epub 2021 Jun 29. Br J Pharmacol. 2021. PMID: 33837969 Free PMC article.
Reinstatement of synaptic plasticity in the aging brain through specific dopamine transporter inhibition.
Lubec J, Kalaba P, Hussein AM, Feyissa DD, Kotob MH, Mahmmoud RR, Wieder O, Garon A, Sagheddu C, Ilic M, Dragačević V, Cybulska-Klosowicz A, Zehl M, Wackerlig J, Sartori SB, Ebner K, Kouhnavardi S, Roller A, Gajic N, Pistis M, Singewald N, Leban JJ, Korz V, Malikovic J, Plasenzotti R, Sitte HH, Monje FJ, Langer T, Urban E, Pifl C, Lubec G. Lubec J, et al. Among authors: sagheddu c. Mol Psychiatry. 2021 Dec;26(12):7076-7090. doi: 10.1038/s41380-021-01214-x. Mol Psychiatry. 2021. PMID: 34244620
32 results