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The TINCR ubiquitin-like microprotein is a tumor suppressor in squamous cell carcinoma.
Morgado-Palacin L, Brown JA, Martinez TF, Garcia-Pedrero JM, Forouhar F, Quinn SA, Reglero C, Vaughan J, Heydary YH, Donaldson C, Rodriguez-Perales S, Allonca E, Granda-Diaz R, Fernandez AF, Fraga MF, Kim AL, Santos-Juanes J, Owens DM, Rodrigo JP, Saghatelian A, Ferrando AA. Morgado-Palacin L, et al. Among authors: saghatelian a. Nat Commun. 2023 Mar 10;14(1):1328. doi: 10.1038/s41467-023-36713-8. Nat Commun. 2023. PMID: 36899004 Free PMC article.
HtrA1 Proteolysis of ApoE In Vitro Is Allele Selective.
Chu Q, Diedrich JK, Vaughan JM, Donaldson CJ, Nunn MF, Lee KF, Saghatelian A. Chu Q, et al. Among authors: saghatelian a. J Am Chem Soc. 2016 Aug 3;138(30):9473-8. doi: 10.1021/jacs.6b03463. Epub 2016 Jul 19. J Am Chem Soc. 2016. PMID: 27379525 Free PMC article.
Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models.
Svensson RU, Parker SJ, Eichner LJ, Kolar MJ, Wallace M, Brun SN, Lombardo PS, Van Nostrand JL, Hutchins A, Vera L, Gerken L, Greenwood J, Bhat S, Harriman G, Westlin WF, Harwood HJ Jr, Saghatelian A, Kapeller R, Metallo CM, Shaw RJ. Svensson RU, et al. Among authors: saghatelian a. Nat Med. 2016 Oct;22(10):1108-1119. doi: 10.1038/nm.4181. Epub 2016 Sep 19. Nat Med. 2016. PMID: 27643638 Free PMC article.
Identification of Microprotein-Protein Interactions via APEX Tagging.
Chu Q, Rathore A, Diedrich JK, Donaldson CJ, Yates JR 3rd, Saghatelian A. Chu Q, et al. Among authors: saghatelian a. Biochemistry. 2017 Jul 5;56(26):3299-3306. doi: 10.1021/acs.biochem.7b00265. Epub 2017 Jun 7. Biochemistry. 2017. PMID: 28589727 Free PMC article.
MIEF1 Microprotein Regulates Mitochondrial Translation.
Rathore A, Chu Q, Tan D, Martinez TF, Donaldson CJ, Diedrich JK, Yates JR 3rd, Saghatelian A. Rathore A, et al. Among authors: saghatelian a. Biochemistry. 2018 Sep 25;57(38):5564-5575. doi: 10.1021/acs.biochem.8b00726. Epub 2018 Sep 14. Biochemistry. 2018. PMID: 30215512 Free PMC article.
162 results