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FIT2 is an acyl-coenzyme A diphosphatase crucial for endoplasmic reticulum homeostasis.
Becuwe M, Bond LM, Pinto AFM, Boland S, Mejhert N, Elliott SD, Cicconet M, Graham MM, Liu XN, Ilkayeva O, Saghatelian A, Walther TC, Farese RV Jr. Becuwe M, et al. Among authors: saghatelian a. J Cell Biol. 2020 Oct 5;219(10):e202006111. doi: 10.1083/jcb.202006111. J Cell Biol. 2020. PMID: 32915949 Free PMC article.
Genetic Liver-Specific AMPK Activation Protects against Diet-Induced Obesity and NAFLD.
Garcia D, Hellberg K, Chaix A, Wallace M, Herzig S, Badur MG, Lin T, Shokhirev MN, Pinto AFM, Ross DS, Saghatelian A, Panda S, Dow LE, Metallo CM, Shaw RJ. Garcia D, et al. Among authors: saghatelian a. Cell Rep. 2019 Jan 2;26(1):192-208.e6. doi: 10.1016/j.celrep.2018.12.036. Cell Rep. 2019. PMID: 30605676 Free PMC article.
AIG1 and ADTRP are endogenous hydrolases of fatty acid esters of hydroxy fatty acids (FAHFAs) in mice.
Erikci Ertunc M, Kok BP, Parsons WH, Wang JG, Tan D, Donaldson CJ, Pinto AFM, Vaughan JM, Ngo N, Lum KM, Henry CL, Coppola AR, Niphakis MJ, Cravatt BF, Saez E, Saghatelian A. Erikci Ertunc M, et al. Among authors: saghatelian a. J Biol Chem. 2020 May 1;295(18):5891-5905. doi: 10.1074/jbc.RA119.012145. Epub 2020 Mar 9. J Biol Chem. 2020. PMID: 32152231 Free PMC article.
Directed remodeling of the mouse gut microbiome inhibits the development of atherosclerosis.
Chen PB, Black AS, Sobel AL, Zhao Y, Mukherjee P, Molparia B, Moore NE, Aleman Muench GR, Wu J, Chen W, Pinto AFM, Maryanoff BE, Saghatelian A, Soroosh P, Torkamani A, Leman LJ, Ghadiri MR. Chen PB, et al. Among authors: saghatelian a. Nat Biotechnol. 2020 Nov;38(11):1288-1297. doi: 10.1038/s41587-020-0549-5. Epub 2020 Jun 15. Nat Biotechnol. 2020. PMID: 32541956 Free PMC article.
Serine restriction alters sphingolipid diversity to constrain tumour growth.
Muthusamy T, Cordes T, Handzlik MK, You L, Lim EW, Gengatharan J, Pinto AFM, Badur MG, Kolar MJ, Wallace M, Saghatelian A, Metallo CM. Muthusamy T, et al. Among authors: saghatelian a. Nature. 2020 Oct;586(7831):790-795. doi: 10.1038/s41586-020-2609-x. Epub 2020 Aug 12. Nature. 2020. PMID: 32788725 Free PMC article.
Nano-scale resolution of native retinal rod disk membranes reveals differences in lipid composition.
Sander CL, Sears AE, Pinto AFM, Choi EH, Kahremany S, Gao F, Salom D, Jin H, Pardon E, Suh S, Dong Z, Steyaert J, Saghatelian A, Skowronska-Krawczyk D, Kiser PD, Palczewski K. Sander CL, et al. Among authors: saghatelian a. J Cell Biol. 2021 Aug 2;220(8):e202101063. doi: 10.1083/jcb.202101063. Epub 2021 Jun 16. J Cell Biol. 2021. PMID: 34132745 Free PMC article.
Inhibition of ceramide accumulation in AdipoR1-/- mice increases photoreceptor survival and improves vision.
Lewandowski D, Foik AT, Smidak R, Choi EH, Zhang J, Hoang T, Tworak A, Suh S, Leinonen H, Dong Z, Pinto AF, Tom E, Luu J, Lee J, Ma X, Bieberich E, Blackshaw S, Saghatelian A, Lyon DC, Skowronska-Krawczyk D, Tabaka M, Palczewski K. Lewandowski D, et al. Among authors: saghatelian a. JCI Insight. 2022 Feb 22;7(4):e156301. doi: 10.1172/jci.insight.156301. JCI Insight. 2022. PMID: 35015730 Free PMC article.
Diet and feeding pattern modulate diurnal dynamics of the ileal microbiome and transcriptome.
Dantas Machado AC, Brown SD, Lingaraju A, Sivaganesh V, Martino C, Chaix A, Zhao P, Pinto AFM, Chang MW, Richter RA, Saghatelian A, Saltiel AR, Knight R, Panda S, Zarrinpar A. Dantas Machado AC, et al. Among authors: saghatelian a. Cell Rep. 2022 Jul 5;40(1):111008. doi: 10.1016/j.celrep.2022.111008. Cell Rep. 2022. PMID: 35793637 Free PMC article.
162 results