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Improvement of Aglycone π-Stacking Yields Nanomolar to Sub-nanomolar FimH Antagonists.
Schönemann W, Cramer J, Mühlethaler T, Fiege B, Silbermann M, Rabbani S, Dätwyler P, Zihlmann P, Jakob RP, Sager CP, Smieško M, Schwardt O, Maier T, Ernst B. Schönemann W, et al. Among authors: sager cp. ChemMedChem. 2019 Apr 3;14(7):749-757. doi: 10.1002/cmdc.201900051. Epub 2019 Feb 22. ChemMedChem. 2019. PMID: 30710416
The price of flexibility - a case study on septanoses as pyranose mimetics.
Sager CP, Fiege B, Zihlmann P, Vannam R, Rabbani S, Jakob RP, Preston RC, Zalewski A, Maier T, Peczuh MW, Ernst B. Sager CP, et al. Chem Sci. 2017 Nov 8;9(3):646-654. doi: 10.1039/c7sc04289b. eCollection 2018 Jan 21. Chem Sci. 2017. PMID: 29629131 Free PMC article.
What contributes to an effective mannose recognition domain?
Sager CP, Eriş D, Smieško M, Hevey R, Ernst B. Sager CP, et al. Beilstein J Org Chem. 2017 Dec 4;13:2584-2595. doi: 10.3762/bjoc.13.255. eCollection 2017. Beilstein J Org Chem. 2017. PMID: 29259668 Free PMC article. Review.
Biochemical analyses and molecular modeling explain the functional loss of 17β-hydroxysteroid dehydrogenase 3 mutant G133R in three Tunisian patients with 46, XY Disorders of Sex Development.
Engeli RT, Rhouma BB, Sager CP, Tsachaki M, Birk J, Fakhfakh F, Keskes L, Belguith N, Odermatt A. Engeli RT, et al. Among authors: sager cp. J Steroid Biochem Mol Biol. 2016 Jan;155(Pt A):147-54. doi: 10.1016/j.jsbmb.2015.10.023. Epub 2015 Nov 3. J Steroid Biochem Mol Biol. 2016. PMID: 26545797
LST-3TM12 is a member of the OATP1B family and a functional transporter.
Malagnino V, Hussner J, Seibert I, Stolzenburg A, Sager CP, Meyer Zu Schwabedissen HE. Malagnino V, et al. Among authors: sager cp. Biochem Pharmacol. 2018 Feb;148:75-87. doi: 10.1016/j.bcp.2017.12.012. Epub 2017 Dec 15. Biochem Pharmacol. 2018. PMID: 29248594
16 results