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Page 1
The effect of Syntex adjuvant formulation (SAF-m) on humoral immunity to the influenza virus in the mouse.
Hjorth RN, Bonde GM, Piner ED, Goldberg KM, Levner MH. Hjorth RN, et al. Vaccine. 1997 Apr;15(5):541-6. doi: 10.1016/s0264-410x(97)00216-8. Vaccine. 1997. PMID: 9160522
Syntex adjuvant in its microfluidized form (SAF-m) was equal to or superior to Freund's complete adjuvant in stimulating an enhanced hemagglutination inhibition (HI) antibody response in mice to trivalent influenza virus vaccine (TIV). ...
Syntex adjuvant in its microfluidized form (SAF-m) was equal to or superior to Freund's complete adjuvant in stimulating an en …
Active specific immunotherapy of metastatic melanoma with an antiidiotype vaccine: a phase I/II trial of I-Mel-2 plus SAF-m.
Quan WD Jr, Dean GE, Spears L, Spears CP, Groshen S, Merritt JA, Mitchell MS. Quan WD Jr, et al. J Clin Oncol. 1997 May;15(5):2103-10. doi: 10.1200/JCO.1997.15.5.2103. J Clin Oncol. 1997. PMID: 9164224 Clinical Trial.
Grade III myalgias/arthralgias and headaches required dose reduction of SAF-m in eight patients at the 250-microgram dose. No treatment-related death occurred. ...CONCLUSION: I-Mel-2 antiidiotype vaccine was safe, tolerated best at the 100-microgram dose of SAF …
Grade III myalgias/arthralgias and headaches required dose reduction of SAF-m in eight patients at the 250-microgram dose. No …
Immune responses induced by prototype vaccines for AIDS in rhesus monkeys.
Ohkawa S, Wilson LA, Larosa G, Javaherian K, Martin LN, Murphey-Corb M. Ohkawa S, et al. AIDS Res Hum Retroviruses. 1994 Jan;10(1):27-38. doi: 10.1089/aid.1994.10.27. AIDS Res Hum Retroviruses. 1994. PMID: 8179961
A battery of assay systems was used to profile both humoral and cell-mediated immune responses induced by immunization with candidate vaccines consisting of recombinant simian immunodeficiency virus (SIV) glycoproteins rgp110 (nondenatured) with SAF-M adjuvant (gp11 …
A battery of assay systems was used to profile both humoral and cell-mediated immune responses induced by immunization with candidate vaccin …
Relevance of the guinea-pig necrotic inflammation footpad reaction to safety concerns with MDP-based adjuvants.
Hjorth RN, Bonde GM, Piner ED, Goldberg KM, Levner MH, Hung PP. Hjorth RN, et al. Vaccine. 1994 Jun;12(8):687-90. doi: 10.1016/0264-410x(94)90217-8. Vaccine. 1994. PMID: 8091845
The reaction was also caused to a significantly lesser degree by a gluteal injection of the threonyl-MDP component of Syntex adjuvant SAF-m. Elicitation of the reaction in responsive animals was absolutely dependent on the presence of both FIA and M. tuberculosis at …
The reaction was also caused to a significantly lesser degree by a gluteal injection of the threonyl-MDP component of Syntex adjuvant SAF …
Vaccinating guinea pigs with recombinant glycoprotein D of herpes simplex virus in an efficacious adjuvant formulation elicits protection against vaginal infection.
Byars NE, Fraser-Smith EB, Pecyk RA, Welch M, Nakano G, Burke RL, Hayward AR, Allison AC. Byars NE, et al. Vaccine. 1994;12(3):200-9. doi: 10.1016/0264-410x(94)90195-3. Vaccine. 1994. PMID: 8165851
Guinea pigs were immunized with glycoprotein gD-2t in SAF-m or saline, then challenged with herpes simplex virus, type 2 (HSV-2). ...MHC II-restricted, gD-2t-specific cytotoxic T cells were induced in guinea pigs vaccinated with gD-2t in SAF-m. Thus, i …
Guinea pigs were immunized with glycoprotein gD-2t in SAF-m or saline, then challenged with herpes simplex virus, type 2 (HSV- …
Immunogenicity of recombinant adenovirus-human immunodeficiency virus vaccines in chimpanzees following intranasal administration.
Lubeck MD, Natuk RJ, Chengalvala M, Chanda PK, Murthy KK, Murthy S, Mizutani S, Lee SG, Wade MS, Bhat BM, et al. Lubeck MD, et al. AIDS Res Hum Retroviruses. 1994 Nov;10(11):1443-9. doi: 10.1089/aid.1994.10.1443. AIDS Res Hum Retroviruses. 1994. PMID: 7888199
Administration of a gp160 subunit vaccine (baculovirus derived) in SAF-m 24 weeks later boosted broadly neutralizing serum antibodies that peaked within 1 month of the injection. ...
Administration of a gp160 subunit vaccine (baculovirus derived) in SAF-m 24 weeks later boosted broadly neutralizing serum ant …
Vaccination and periodontitis: myth or reality.
Page RC. Page RC. J Int Acad Periodontol. 2000 Apr;2(2):31-43. J Int Acad Periodontol. 2000. PMID: 12666959
Using ligature-induced periodontitis in the non-human primate Macaca fascicularis as a model, we immunised 10 animals using intact killed P. gingivalis and SAF-M adjuvant and 10 controls using adjuvant only. The vaccine, containing 250 microg protein/ml, was injecte …
Using ligature-induced periodontitis in the non-human primate Macaca fascicularis as a model, we immunised 10 animals using intact killed P. …
Vaccine evaluation studies of replication-defective SIVsmB7.
Kraiselburd EN, Salaman A, Beltrán M, Rivera M, Oliver J, Kessler M, Knezevich M, Rodriguez A, Bilska M, Montefiori D, Torres-Bauza LJ, Martinez I. Kraiselburd EN, et al. Cell Mol Biol (Noisy-le-grand). 1997 Nov;43(7):915-24. Cell Mol Biol (Noisy-le-grand). 1997. PMID: 9449524
Animals were immunized in three groups: group A was primed with cell-associated SIVsmB7 and boosted with cell-free SIVsmB7; group B was primed with cell-free SIVsmB7 and boosted with cell-free SIVsmB7 conjugated to iron oxide microbeads; group C was primed with cell-free SIVsmB7 …
Animals were immunized in three groups: group A was primed with cell-associated SIVsmB7 and boosted with cell-free SIVsmB7; group B was prim …
Common risk variants in NPHS1 and TNFSF15 are associated with childhood steroid-sensitive nephrotic syndrome.
Jia X, Yamamura T, Gbadegesin R, McNulty MT, Song K, Nagano C, Hitomi Y, Lee D, Aiba Y, Khor SS, Ueno K, Kawai Y, Nagasaki M, Noiri E, Horinouchi T, Kaito H, Hamada R, Okamoto T, Kamei K, Kaku Y, Fujimaru R, Tanaka R, Shima Y; Research Consortium on Genetics of Childhood Idiopathic Nephrotic Syndrome in Japan; Baek J, Kang HG, Ha IS, Han KH, Yang EM; Korean Consortium of Hereditary Renal Diseases in Children; Abeyagunawardena A, Lane B, Chryst-Stangl M, Esezobor C, Solarin A; Midwest Pediatric Nephrology Consortium (Genetics of Nephrotic Syndrome Study Group); Dossier C, Deschênes G; NEPHROVIR; Vivarelli M, Debiec H, Ishikura K, Matsuo M, Nozu K, Ronco P, Cheong HI, Sampson MG, Tokunaga K, Iijima K. Jia X, et al. Kidney Int. 2020 Nov;98(5):1308-1322. doi: 10.1016/j.kint.2020.05.029. Epub 2020 Jun 14. Kidney Int. 2020. PMID: 32554042 Free PMC article.
15 results