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Metallodrugs are unique: opportunities and challenges of discovery and development.
Anthony EJ, Bolitho EM, Bridgewater HE, Carter OWL, Donnelly JM, Imberti C, Lant EC, Lermyte F, Needham RJ, Palau M, Sadler PJ, Shi H, Wang FX, Zhang WY, Zhang Z. Anthony EJ, et al. Among authors: sadler pj. Chem Sci. 2020 Nov 12;11(48):12888-12917. doi: 10.1039/d0sc04082g. Chem Sci. 2020. PMID: 34123239 Free PMC article. Review.
Approaches to the design of catalytic metallodrugs.
Soldevila-Barreda JJ, Sadler PJ. Soldevila-Barreda JJ, et al. Among authors: sadler pj. Curr Opin Chem Biol. 2015 Apr;25:172-83. doi: 10.1016/j.cbpa.2015.01.024. Epub 2015 Mar 12. Curr Opin Chem Biol. 2015. PMID: 25765750 Free article. Review.
In-Cell Activation of Organo-Osmium(II) Anticancer Complexes.
Needham RJ, Sanchez-Cano C, Zhang X, Romero-Canelón I, Habtemariam A, Cooper MS, Meszaros L, Clarkson GJ, Blower PJ, Sadler PJ. Needham RJ, et al. Among authors: sadler pj. Angew Chem Int Ed Engl. 2017 Jan 19;56(4):1017-1020. doi: 10.1002/anie.201610290. Epub 2016 Dec 21. Angew Chem Int Ed Engl. 2017. PMID: 28000997 Free PMC article.
Supramolecular Photoactivatable Anticancer Hydrogels.
Venkatesh V, Mishra NK, Romero-Canelón I, Vernooij RR, Shi H, Coverdale JPC, Habtemariam A, Verma S, Sadler PJ. Venkatesh V, et al. Among authors: sadler pj. J Am Chem Soc. 2017 Apr 26;139(16):5656-5659. doi: 10.1021/jacs.7b00186. Epub 2017 Apr 17. J Am Chem Soc. 2017. PMID: 28414222
New activation mechanism for half-sandwich organometallic anticancer complexes.
Banerjee S, Soldevila-Barreda JJ, Wolny JA, Wootton CA, Habtemariam A, Romero-Canelón I, Chen F, Clarkson GJ, Prokes I, Song L, O'Connor PB, Schünemann V, Sadler PJ. Banerjee S, et al. Among authors: sadler pj. Chem Sci. 2018 Mar 1;9(12):3177-3185. doi: 10.1039/c7sc05058e. eCollection 2018 Mar 28. Chem Sci. 2018. PMID: 29732100 Free PMC article.
476 results