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Disruption of SUV39H1-Mediated H3K9 Methylation Sustains CAR T-cell Function.
Jain N, Zhao Z, Koche RP, Antelope C, Gozlan Y, Montalbano A, Brocks D, Lopez M, Dobrin A, Shi Y, Gunset G, Giavridis T, Sadelain M. Jain N, et al. Among authors: sadelain m. Cancer Discov. 2024 Jan 12;14(1):142-157. doi: 10.1158/2159-8290.CD-22-1319. Cancer Discov. 2024. PMID: 37934007
Targeted elimination of prostate cancer by genetically directed human T lymphocytes.
Gade TP, Hassen W, Santos E, Gunset G, Saudemont A, Gong MC, Brentjens R, Zhong XS, Stephan M, Stefanski J, Lyddane C, Osborne JR, Buchanan IM, Hall SJ, Heston WD, Rivière I, Larson SM, Koutcher JA, Sadelain M. Gade TP, et al. Among authors: sadelain m. Cancer Res. 2005 Oct 1;65(19):9080-8. doi: 10.1158/0008-5472.CAN-05-0436. Cancer Res. 2005. PMID: 16204083
The basic principles of chimeric antigen receptor design.
Sadelain M, Brentjens R, Rivière I. Sadelain M, et al. Cancer Discov. 2013 Apr;3(4):388-98. doi: 10.1158/2159-8290.CD-12-0548. Epub 2013 Apr 2. Cancer Discov. 2013. PMID: 23550147 Free PMC article. Review.
Mesothelin-Targeted CARs: Driving T Cells to Solid Tumors.
Morello A, Sadelain M, Adusumilli PS. Morello A, et al. Among authors: sadelain m. Cancer Discov. 2016 Feb;6(2):133-46. doi: 10.1158/2159-8290.CD-15-0583. Epub 2015 Oct 26. Cancer Discov. 2016. PMID: 26503962 Free PMC article. Review.
Donor CD19 CAR T cells exert potent graft-versus-lymphoma activity with diminished graft-versus-host activity.
Ghosh A, Smith M, James SE, Davila ML, Velardi E, Argyropoulos KV, Gunset G, Perna F, Kreines FM, Levy ER, Lieberman S, Jay HV, Tuckett AZ, Zakrzewski JL, Tan L, Young LF, Takvorian K, Dudakov JA, Jenq RR, Hanash AM, Motta AC, Murphy GF, Liu C, Schietinger A, Sadelain M, van den Brink MR. Ghosh A, et al. Among authors: sadelain m. Nat Med. 2017 Feb;23(2):242-249. doi: 10.1038/nm.4258. Epub 2017 Jan 9. Nat Med. 2017. PMID: 28067900 Free PMC article.
305 results