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Stem cell mobilizers targeting chemokine receptor CXCR4: renoprotective application in acute kidney injury.
J Med Chem. 2015 Mar 12;58(5):2315-25. doi: 10.1021/jm501769r. Epub 2015 Mar 2.
J Med Chem. 2015.
PMID: 25686267
Discovery of 1-(2,4-dichlorophenyl)-N-(piperidin-1-yl)-4-((pyrrolidine-1-sulfonamido)methyl)-5-(5-((4-(trifluoromethyl)phenyl)ethynyl)thiophene-2-yl)-1H-pyrazole-3-carboxamide as a novel peripherally restricted cannabinoid-1 receptor antagonist with significant weight-loss efficacy in diet-induced obese mice.
Chang CP, Wu CH, Song JS, Chou MC, Wong YC, Lin Y, Yeh TK, Sadani AA, Ou MH, Chen KH, Chen PH, Kuo PC, Tseng CT, Chang KH, Tseng SL, Chao YS, Hung MS, Shia KS.
Chang CP, et al. Among authors: sadani aa.
J Med Chem. 2013 Dec 27;56(24):9920-33. doi: 10.1021/jm401158e. Epub 2013 Dec 4.
J Med Chem. 2013.
PMID: 24224693
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Function-oriented development of CXCR4 antagonists as selective human immunodeficiency virus (HIV)-1 entry inhibitors.
Wu CH, Wang CJ, Chang CP, Cheng YC, Song JS, Jan JJ, Chou MC, Ke YY, Ma J, Wong YC, Hsieh TC, Tien YC, Gullen EA, Lo CF, Cheng CY, Liu YW, Sadani AA, Tsai CH, Hsieh HP, Tsou LK, Shia KS.
Wu CH, et al. Among authors: sadani aa.
J Med Chem. 2015 Feb 12;58(3):1452-65. doi: 10.1021/jm501772w. Epub 2015 Jan 28.
J Med Chem. 2015.
PMID: 25584630
Free PMC article.
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Bromomethylthioindole Inspired Carbazole Hybrids as Promising Class of Anti-MRSA Agents.
Cheng CY, Chang CP, Lauderdale TY, Yu GY, Lee JC, Jhang YW, Wu CH, Ke YY, Sadani AA, Yeh CF, Huang IW, Kuo YP, Tsai DJ, Yeh TK, Tseng CT, Song JS, Liu YW, Tsou LK, Shia KS.
Cheng CY, et al. Among authors: sadani aa.
ACS Med Chem Lett. 2016 Oct 21;7(12):1191-1196. doi: 10.1021/acsmedchemlett.6b00289. eCollection 2016 Dec 8.
ACS Med Chem Lett. 2016.
PMID: 27994762
Free PMC article.
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Ureas: Applications in Drug Design.
Jagtap AD, Kondekar NB, Sadani AA, Chern JW.
Jagtap AD, et al. Among authors: sadani aa.
Curr Med Chem. 2017;24(6):622-651. doi: 10.2174/0929867323666161129124915.
Curr Med Chem. 2017.
PMID: 27897114
Review.
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Organocatalytic enantioselective domino Michael-aldol condensation of 5-oxoalkanal and alpha,beta-unsaturated aldehydes. Efficient assembly of densely functionalized cyclohexenes.
Hong BC, Nimje RY, Sadani AA, Liao JH.
Hong BC, et al. Among authors: sadani aa.
Org Lett. 2008 Jun 19;10(12):2345-8. doi: 10.1021/ol8005369. Epub 2008 May 17.
Org Lett. 2008.
PMID: 18484729
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